Characterization and Support for Neurodevelopmental Disorders Associated With Congenital Heart Defects

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for children aged 3 to 11 with a critical congenital heart defect who had heart surgery in their first three months of life. Both biological parents take part too.

Életkor

3 to 11 years

Nem

All

A betegség stádiuma

Critical congenital heart defect (a serious heart problem present from birth).

Korábbi kezelés

Must have had heart surgery during the first three months of life.

A részvétel fő kizáró okai

• A genetic anomaly or malformation syndrome linked to brain development problems, found before joining
• The child's development assessment cannot be done
• Parents or child do not understand French well
• Parents are not the biological parents
• Not covered by social security or a similar scheme

A regiszter feltételei, szó szerint

Nézd meg, megfelelhetsz-e

Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.

• 3 és 11 év között vagy?IgenNem

Mit akar kideríteni a vizsgálat

The leading cause of birth defects, Congenital Heart Defects (CHD) affect 12 million people worldwide and 41,000 newborns/year in Europe. It's a major cause of life-long morbidity and mortality, and a crucial public health issue. More than 50% of childs born with critical CHD will develop Neurodevelopmental Disorders (NDs), requiring specific care and impairing quality of life. NDs corresponds to early and lasting disturbances in cognitive, affective and behavioral development, linked to abnormalities in brain development. They are heterogeneous, affecting language, learning, motor skills, intellectual efficiency, social cognition, attention, memory and executive functions, and are associated with psychosocial difficulties (adaptive behavior, social interactions). This hidden handicap is the main long-term sequels of CHD, even before cardiovascular sequels, in individuals who often underwent multiple heart operations in early childhood. NDs concern not only complex CHD, but also simple CHD repaired in childhood and considered cured.

A vizsgálat 2 csoportja

• CATAMARAN - Pediatrics - Interdisciplinary programme - Nantes OnlyEgyéb csoport

  The study population will consist of 201 children aged 3 to 11 and their two parents.

  Kezelés: Blood sampling, Assessment of neurodevelopment (Nantes) és Assessment of the parental stress

• CATAMARAN - Pediatrics - Unique neuropsychological assessment Associated centers (including Nantes)Egyéb csoport

  The study population will consist of 201 children aged 3 to 11 and their two parents.

  Kezelés: Blood sampling, Assessment of neurodevelopment (CA) és Assessment of the parental stress