Calibr-Ì: Comparative Evaluation of Phantomless Calibration Methods to Quantify Bone Mineral Density for Opportunistic Analysis of CT Scans
A legfontosabb adatok
- Hol
- Bologna (Olaszország)A helyszín megnézése
AI-kivonat: kiket keres a vizsgálat
A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.
A vizsgálat olyan felnőtteket keres, akiknek bármilyen okból CT-vizsgálatot végeznek az ágyéki gerincről vagy a hasról. A vizsgálat a csontsűrűség CT-felvételből történő mérésének módszereit hasonlítja össze.
- Életkor
- 18 éves vagy idősebb
- Nem
- Férfiak és nők is részt vehetnek
- A betegség stádiuma
- Nem kell hozzá konkrét betegség. A CT-felvételen látszania kell a teljes ágyéki gerincnek (L1–L5), a gerinc melletti izmoknak, a hasi főütőérnek és a bőr alatti zsírszövetnek.
A részvétel fő kizáró okai
- Általános akadályok a CT-vizsgálat elvégzésére, például terhesség, vagy a testsúly vagy testméret meghaladja a készülék határait
- Az ágyéki gerinc súlyos kopásos elváltozásai
- Az ágyéki gerinc súlyos elgörbülése (scoliosis)
- Műtéti fém implantátum, amely akadályozza a jó CT-felvételt
- Jelenlegi vagy a közelmúltban lezajlott daganatos betegség
Gépi kiolvasás: 2026. november 12.
Helyszínek itt: Olaszország
- The Rizzoli Orthopaedic InstituteBologna, OlaszországContact: Alberto Bazzocchi, MD, PhDRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Istituto Ortopedico Rizzoli
- Azonosító
- NCT06454617
- A regiszteradat frissítve
- 2025. június 10.
- Eredeti leírás
Osteoporosis is a systemic disease characterized by a reduction in bone mineral density (BMD) and qualitative alteration of the skeleton, resulting in increased bone fragility and fracture risk. The epidemiological impact of osteoporosis is extremely high. Proper diagnosis and clinical management of osteoporosis are critical to reducing the incidence of fragility fractures and preventing their complications. The diagnosis is generally confirmed by instrumental analysis of bone mineral density. The standard method is X-ray bone densitometry (DXA), which allows diagnosis based on criteria defined by the World Health Organization (WHO) by virtue of the T-score. DXA is a relatively quick and inexpensive examination with low exposure to ionizing radiation. However, this method has limitations in detecting fracture risk, and in addition, not all patients are properly referred for DXA services, which, among other things, require specific criteria to be reimbursed by the National Health System. Currently, computed tomography (CT) scanning is the most widely used three-dimensional diagnostic modality in clinical practice, and the number of investigations performed in high-income countries is continuously growing. Quantitative assessment of bone mineral density by CT is possible by proper calibration of the machine for the purpose of converting the CT numbers (or Hounsfield units) measured by the scanner into BMD units.A teljes eredeti leírásKevesebb
Comparative Evaluation of Phantomless Calibration Methods to Quantify Bone Mineral Density for Opportunistic Analysis of CT Scans
Osteoporosis is a systemic disease characterized by a reduction in bone mineral density (BMD) and qualitative alteration of the skeleton, resulting in increased bone fragility and fracture risk. The epidemiological impact of osteoporosis is extremely high. Proper diagnosis and clinical management of osteoporosis are critical to reducing the incidence of fragility fractures and preventing their complications. The diagnosis is generally confirmed by instrumental analysis of bone mineral density. The standard method is X-ray bone densitometry (DXA), which allows diagnosis based on criteria defined by the World Health Organization (WHO) by virtue of the T-score. DXA is a relatively quick and inexpensive examination with low exposure to ionizing radiation. However, this method has limitations in detecting fracture risk, and in addition, not all patients are properly referred for DXA services, which, among other things, require specific criteria to be reimbursed by the National Health System. Currently, computed tomography (CT) scanning is the most widely used three-dimensional diagnostic modality in clinical practice, and the number of investigations performed in high-income countries is continuously growing. Quantitative assessment of bone mineral density by CT is possible by proper calibration of the machine for the purpose of converting the CT numbers (or Hounsfield units) measured by the scanner into BMD units.
Bevonási feltételek: Both sexes; All ethnicities; Age equal or above 18 years; Any clinical indication (no specific pathology is required) for a CT scan of the lumbosacral spine or abdomen in which the entire lumbar spine (L1 to L5), paravertebral muscles, abdominal aorta, and subcutaneous adipose tissue are visible; Ability to give informed consent.
Kizáró feltételek: Surgical hardware that prevents adequate CT scanning; General contraindications to CT examination, including pregnancy or body weight/size exceeding scanner limits; Severe degenerative manifestations of the lumbosacral spine; Severe scoliosis of the lumbosacral spine; Oncologic pathology in progress or in recent history; Any other situation deemed incompatible with the study by the designated physician or investigator.