Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator
A legfontosabb adatok
- Hol
- Jacksonville (Egyesült Államok)A helyszín megnézése
- Fázis
- Korai 1. fázis
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 70 év között vagy?
Forrás: NCT06684470: ki vehet részt
Helyszínek itt: Egyesült Államok
- Mayo ClinicJacksonville, Egyesült ÁllamokContact: Jessica C Petrov, M.D.Résztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Mayo Clinic
- Azonosító
- NCT06684470
- A regiszteradat frissítve
- 2025. december 18.
- Eredeti leírás
The purpose of this research is to study the added benefit of treating IBS symptoms with a medication called mirtazapine in treating IBS symptoms when paired with a low-FODMAP diet compared to a low-FODMAP diet alone. FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. These are short-chain carbohydrates that can cause digestive distress in some people.A teljes eredeti leírásKevesebb
The purpose of this research is to study the added benefit of treating IBS symptoms with a medication called mirtazapine in treating IBS symptoms when paired with a low-FODMAP diet compared to a low-FODMAP diet alone. FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. These are short-chain carbohydrates that can cause digestive distress in some people.
You have been asked to take part in this research because you have symptoms of diarrhea-predominant irritable bowel syndrome that may respond to treatment with a combination of a medication called mirtazapine and a low-FODMAP diet.
Bevonási feltételek: Participants must meet all of the inclusion criteria to participate in this study:; Adults (ages 18-70); Score of >175 on the IBS-SSS questionnaire; Must meet Rome IV criteria for IBS-D; If subject is of reproductive capability a negative urine pregnancy test must be available prior to entering the study; Ability to understand study procedures and to comply with them for the entire length of the study.
Kizáró feltételek: All candidates meeting any of the below exclusion criteria at baseline will be excluded from study participation:; Score of < 175 on the IBS-SSS; Prior diagnoses of: known celiac disease, small intestinal bacterial overgrowth, inflammatory bowel disease, or microscopic colitis; Ongoing significant anxiety or depression; A history of a known side effect to mirtazapine; Prior treatment with a low FODMAP diet or mirtazapine without clinical benefit; Active alcohol or drug abuse; Inability to read or understand the consent form; Any other medical or psychological reason that would prevent active participation in a research study; Pregnant females.