Italian Adaptation and Validation of Functional and Behavioural Scales for Subjective Cognitive Decline, Mild Cognitive Impairment and Mild Dementia.

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for people aged 60 or older without memory or thinking problems, and people with subjective cognitive decline, mild cognitive impairment or mild dementia. It tests Italian versions of questionnaires about daily activities and behaviour.

Életkor

60 years or older

Nem

All sexes

A betegség stádiuma

Healthy older people with a normal Mini Mental State Examination result, or people with subjective cognitive decline (feeling that memory or thinking has worsened), mild cognitive impairment, or mild major neurocognitive disorder (mild dementia).

A részvétel fő kizáró okai

• No family member or caregiver who can judge the person's daily abilities
• Refusing or not able to sign informed consent
• For the patient groups: other neurological or psychiatric conditions that may explain the thinking problems

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

The first aim of the observational study is the translation, cross-cultural adaptation and validation of functional and behavioral scales used in the diagnosis of neurodegenerative diseases, for which a formal version in Italian is not available at present. In particular, the study includes the following functional and behavioral scales: the Katz's index (Basic Activities of Daily Living, BADL), the Lawton and Brody's scale (Instrumental Activities of Daily Living, IADL), the Everyday Cognition questionnaire (E-Cog), the Neuropsychiatric Inventory Questionnaire (NPI-Q) for assessing the Behavioral and Psychological Symptoms of Dementia. Furthermore, a modified Italian version of the Functional Activities Questionnaire (FAQ), which integrates and updates the content of the original items (e.g., addressing the use of technologies, M-FAQ) will be used in the validation study.

A vizsgálat 4 csoportja

• Neurologically unimpaired participants

  i) Age ≥ 60 years; ii) Availability of an informant/caregiver, able to judge their functional abilities; iii) Normal performance on the Mini Mental State Examination (Folstein et al. 1975; Foderaro et al., 2022).

• Subjective Cognitive Decline (SCD)

  i) Age ≥ 60 years; ii) Availability of an informant/caregiver, able to judge their functional abilities. iii) Conditions consistent with Subjective Cognitive Decline according to Jessen et al. (2014)

• Mild Cognitive Impairment (MCI)

  i) Age ≥ 60 years; ii) Availability of an informant/caregiver, able to judge their functional abilities. iii) Conditions consistent with Mild Cognitive Impairment according to Winblad et al. (2004)

• Major Neurocognitive Disorder

  i) Age ≥ 60 years; ii) Availability of an informant/caregiver, able to judge their functional abilities iii) Conditions consistent with a Mild Major Neurocognitive Disorder according to DSM-5-TR (APA, 2022).