A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
A legfontosabb adatok
- Hol
- Asheville, Atlanta, Austin, Baltimore, Bellaire, Boston, Bowling Green, Canton, Chattanooga, Clearwater, Dallas, Englewood, Farmington Hills, Flint, Florence, Gulfport, Houston, Huntington Beach, Indianapolis, Jacksonville, Kansas City, Las Vegas, Los Angeles, Macon, Mesquite, Metairie, Miami, Monroe, Nashville, New Orleans, Newark, Ocoee, Omaha, Orange, Orlando, Philadelphia, Phoenix, Port Charlotte, Portland, Pottstown, Rochester, Round Rock, Sacramento, Salt Lake City, San Antonio, San Francisco, Sandy City, Santa Clarita, Shreveport, Stockbridge, Summerville, Torrance, Walnut Creek, Washington D.C., West Palm Beach és Wilmington (Egyesült Államok)Mind a 64 helyszín megnézése
- Fázis
- 2. fázis
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 75 év között vagy?
Forrás: NCT06727604: ki vehet részt
Helyszínek itt: Egyesült Államok
- Asheville, North CarolinaHospital not named in the registryRésztvevőt keres
- Atlanta, GeorgiaHospital not named in the registryRésztvevőt keres
- Austin, TexasHospital not named in the registryRésztvevőt keres
- Baltimore, MarylandHospital not named in the registryRésztvevőt keres
- Bellaire, TexasHospital not named in the registryRésztvevőt keres
- Boston, MassachusettsHospital not named in the registryRésztvevőt keres
- Bowling Green, KentuckyHospital not named in the registryRésztvevőt keres
- Canton, OhioHospital not named in the registryRésztvevőt keres
- Chattanooga, TennesseeHospital not named in the registryRésztvevőt keres
- Clearwater, FloridaHospital not named in the registryRésztvevőt keres
- Dallas, TexasHospital not named in the registryRésztvevőt keres
- Dallas, TexasHospital not named in the registryNo longer taking part
- Englewood, ColoradoHospital not named in the registryRésztvevőt keres
- Farmington Hills, MichiganHospital not named in the registryRésztvevőt keres
- Flint, MichiganHospital not named in the registryRésztvevőt keres
- Florence, KentuckyHospital not named in the registryRésztvevőt keres
- Gulfport, MississippiHospital not named in the registryRésztvevőt keres
- Houston, TexasHospital not named in the registryRésztvevőt keres
- Houston, TexasHospital not named in the registryNo longer taking part
- Huntington Beach, CaliforniaHospital not named in the registryRésztvevőt keres
- Indianapolis, IndianaHospital not named in the registryRésztvevőt keres
- Jacksonville, FloridaHospital not named in the registryRésztvevőt keres
- Jacksonville, FloridaHospital not named in the registryRésztvevőt keres
- Kansas City, KansasHospital not named in the registryRésztvevőt keres
- Las Vegas, NevadaHospital not named in the registryRésztvevőt keres
- Los Angeles, CaliforniaHospital not named in the registryRésztvevőt keres
- Los Angeles, CaliforniaHospital not named in the registryRésztvevőt keres
- Macon, GeorgiaHospital not named in the registryRésztvevőt keres
- Mesquite, TexasHospital not named in the registryRésztvevőt keres
- Metairie, LouisianaHospital not named in the registryRésztvevőt keres
- Miami, FloridaHospital not named in the registryRésztvevőt keres
- Miami, FloridaHospital not named in the registryRésztvevőt keres
- Monroe, New YorkHospital not named in the registryRésztvevőt keres
- Nashville, TennesseeHospital not named in the registryRésztvevőt keres
- Nashville, TennesseeHospital not named in the registryRésztvevőt keres
- New Orleans, LouisianaHospital not named in the registryRésztvevőt keres
- Newark, DelawareHospital not named in the registryRésztvevőt keres
- Ocoee, FloridaHospital not named in the registryRésztvevőt keres
- Omaha, NebraskaHospital not named in the registryRésztvevőt keres
- Orange, CaliforniaHospital not named in the registryRésztvevőt keres
- Orlando, FloridaHospital not named in the registryNo longer taking part
- Philadelphia, PennsylvaniaHospital not named in the registryNo longer taking part
- Phoenix, ArizonaHospital not named in the registryRésztvevőt keres
- Phoenix, ArizonaHospital not named in the registryNo longer taking part
- Port Charlotte, FloridaHospital not named in the registryRésztvevőt keres
- Portland, OregonHospital not named in the registryRésztvevőt keres
- Pottstown, PennsylvaniaHospital not named in the registryRésztvevőt keres
- Rochester, MinnesotaHospital not named in the registryRésztvevőt keres
- Round Rock, TexasHospital not named in the registryRésztvevőt keres
- Sacramento, CaliforniaHospital not named in the registryRésztvevőt keres
- Salt Lake City, UtahHospital not named in the registryRésztvevőt keres
- San Antonio, TexasHospital not named in the registryRésztvevőt keres
- San Antonio, TexasHospital not named in the registryRésztvevőt keres
- San Francisco, CaliforniaHospital not named in the registryRésztvevőt keres
- Sandy City, UtahHospital not named in the registryRésztvevőt keres
- Santa Clarita, CaliforniaHospital not named in the registryNo longer taking part
- Shreveport, LouisianaHospital not named in the registryRésztvevőt keres
- Stockbridge, GeorgiaHospital not named in the registryNo longer taking part
- Summerville, South CarolinaHospital not named in the registryRésztvevőt keres
- Torrance, CaliforniaHospital not named in the registryRésztvevőt keres
- Walnut Creek, CaliforniaHospital not named in the registryNo longer taking part
- Washington D.C., District of ColumbiaHospital not named in the registryRésztvevőt keres
- West Palm Beach, FloridaHospital not named in the registryNo longer taking part
- Wilmington, North CarolinaHospital not named in the registryRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Immunovant Sciences GmbH
- Azonosító
- NCT06727604EU 2024-516020-33-00
- A regiszteradat frissítve
- 2026. augusztus 25.
- Eredeti leírás
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.A teljes eredeti leírásKevesebb
A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.
The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or free triiodothyronine [FT3]), free thyroxine (FT4), thyroid-stimulating hormone (TSH), and ATD dose at Week 26.
Bevonási feltételek: Participants with the ability to understand the requirements of the trial, provide written informed consent, and comply with the trial protocol procedures; Male or female participants aged ≥ 18 years; Participants with diagnosis of GD who are hyperthyroid despite ATD treatment; Other, more specific inclusion criteria are defined in the protocol.
Kizáró feltételek: Have previously been successfully treated with radioactive iodine (RAI) therapy or have undergone total thyroidectomy; Have an autoimmune disease other than GD requiring treatment that, in the Investigator's judgment, puts the participant at undue risk; Have moderate-to-severe active thyroid eye disease (TED) and are expected to require immediate surgical intervention and/or are planning corrective surgery/irradiation or medical therapy for TED during study participation; Additional exclusion criteria are defined in the protocol.