Prehabilitation for Lung Cancer Patients Undergoing Lung Resection

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

A vizsgálat olyan felnőtteket keres, akik tüdőrák miatt tüdőműtétre várnak. Négy különböző műtét előtti felkészítést hasonlít össze.

Életkor

18 éves vagy idősebb

Nem

Mindkét nem

A betegség stádiuma

Tüdőrák, a tüdőeltávolító műtétre a Unidade Local de Saúde São João szív- és mellkassebészeti osztályán felvett beteg

Korábbi kezelés

Nem vehet részt más műtét előtti felkészítő programban. Korábban nem volt mellkasi műtétje.

A részvétel fő kizáró okai

• Szív-, vér- vagy idegrendszeri betegség
• Pulmonális hipertónia (tüdőérrendszeri magas vérnyomás) vagy veseelégtelenség
• Korábbi mellkasi műtét vagy a teljes tüdő eltávolítása (pneumectomia)
• Kognitív vagy mentális zavar
• Önálló járásban akadályozottság

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

Lung surgical resection is the gold standard treatment for earlier stages of lung cancer patients. Nevertheless, postoperative pulmonary complications (PPC) are frequent, related to morbidity and mortality, increasing length of hospital stay (LOS), hospital costs, delaying adjuvant treatments, and patients suffering. The PPC often occurs on postoperative days, even after hospital discharge. Prehabilitation might reduce PPC, although few studies have compared the effectiveness of different training protocols, and no information is available regarding the possible benefits of expiratory muscle training. Moreover, there are no comparisons of the cost-benefits of other protocols in patients submitted to lung resection surgery.

A vizsgálat 4 csoportja

• Control Group (CG)Már használt kezelés, összehasonlításként

  Control group will receive a single in-person preoperative education session at the Faculty of Sport of University of Porto, one week after the patient's inclusion in the study. The education session will be delivered for the patient and his/her caregiver or family member. The information that will be delivery is going to be focused on: * Lifestyle changes regarding nutrition and daily physical activity. * Abstinence of the additive behaviors smoking, alcohol, and drug consumption. * Personal hygiene care and hospital routines. * Importance of postoperative physiotherapy. A booklet summarizing the information provided at the education session will be delivered for all participants.

  Kezelés: Education session

• Inspiratory Muscle Training Group (IMT-G)A vizsgált kezelés

  The IMT-G will be submitted to an education session (equal to the CG) plus 2-weeks of inspiratory muscle training (IMT). After the education session, patients will start the IMT program that will last two weeks. The IMT will be 5 days/ week, lasting \~20 minutes, using the PowerBreath KH2 device. All sessions will start with 5 min of stretching exercises and then the IMT. In the first week, the intensity of the PowerBreath KH2 will be set at 50% of the maximal inspiratory pressure (with 12 breaths per minute), and it will be increasing by 10% in the second week (with 15 breaths per minute). Patients will be continuously monitored by an oximeter and modified Borg scale All IMT session will take place at São João Hospital.

  Kezelés: Education session és Inspiratory muscle training group

• Expiratory Muscle Training Group (EMT-G)A vizsgált kezelés

  The EMT-G will be submitted to an education session (equal to the CG) plus 2-weeks of expiratory muscle training (EMT). After the education session, patients will start the EMT that will last two weeks, 5 days a week. The sessions will last \~20 minutes and will be structured as follows: * 5 minutes of stretching exercises * 8 minutes of abdominal resistance exercises (1st week: 2 exercises, 4 sets of 8 repetitions; 2nd week: 2 exercises, 4 sets of 10 repetitions) * 8 minutes of specific EMT using the Philips Respironics Threshold PEP device (Load: 20 cmH2O; 10 expirations for minute) Patients will be continuously monitored by an oximeter and modified Borg scale. All EMT session will take place at São João Hospital.

  Kezelés: Education session és Expiratory muscle training group

• Global Exercise Training Group (GET-G)A vizsgált kezelés

  The GET-G will be submitted to an education session (equal to the CG) plus 2-weeks of physical exercise, 3 sessions per week, 45-60 minutes. The structure is: Warm-up 5 minutes of whole-body stretching exercises Main workout: -Aerobic: Week 1: 20 min of treadmill walking at 70% of the mean speed achieved on the 6-minute walk test and limited by 80% of the max theoretical heart rate. Week 2: 20 min of treadmill walking at 80% of the mean speed achieved on the 6-minute walk test and limited by 80% of the max theoretical heart rate. -Resistance Week 1: 8 exercises, 2 sets of 8-10 repetitions, using body weight and elastic bands. Week 2: 8 exercises, 2 sets of 10-12 repetitions, using body weight and elastic bands Coll-down: 5 min of whole-body stretching exercises, holding the point of feeling lightness discomfort for 15 seconds. Patients will be continuously monitored by an oximeter and modified Borg scale.

  Kezelés: Education session és Global exercise training group