COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults with knee osteoarthritis who are having a planned knee replacement on one side. They must also have pain and arthritis in the other knee.

Életkor

18 years and older

Nem

All sexes

A betegség stádiuma

Primary osteoarthritis with a planned elective knee replacement on one knee only. The other knee must have pain scored above 4/10 and arthritis of Kellgren and Lawrence grade >2-4 on X-ray.

Korábbi kezelés

No injections (steroids/biologics) in the other knee within one year. No previous knee replacement, ORIF, nailing or arthroscopy on either knee.

A részvétel fő kizáró okai

• Arthritis from other causes, such as inflammatory or post traumatic arthritis
• Memory or thinking problems (dementia, Alzheimer's, uncontrolled delirium) that prevent completing the study
• Past or current knee infection, injury or extensor mechanism damage
• Plans for knee replacement on both knees, or on the other knee within the next six months
• Medical reasons that rule out planned knee replacement surgery

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.

A vizsgálat 2 csoportja

• Group A - Corticosteroid InjectionA vizsgált kezelés

  Corticosteroid injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL). The patient will be brought to the regional room where a fully licensed anaesthesiologist will perform standard of care anaesthesia followed by an ultrasound guided intra-articular knee injection with steroid AFTER the spinal neuraxial blockage has already been administered.

  Kezelés: Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).

• Group B - Band-Aid PlacementSzínlelt kezelés, összehasonlításként

  The patient will be brought to the regional room where a fellowship trained interventional pain/regional anaesthesiologist will perform standard of care anaesthesia followed by the application of a band-aid.

  Kezelés: Band-Aid