The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study
A legfontosabb adatok
- Hol
- Milwaukee (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- Medical College of WisconsinMilwaukee, Egyesült ÁllamokContact: Aditya VedantamRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- AO Foundation, AO Spine
- Azonosító
- NCT06839300
- A regiszteradat frissítve
- 2026. október 1.
- Eredeti leírás
To determine the accuracy of serum NF-L and GFAP levels (ie the biomarkers) at different time points postinjury for predicting the severity of neurologic impairment at 6 months postinjury as either motor complete (AIS grade A/B) or motor incomplete (AIS grade C/D) a group of patients who suffer traumatic spinal fracture and/or dislocation of the spinal column but without neurologic injury will be enrolled as non-SCI spine trauma control participants.A teljes eredeti leírásKevesebb
To determine the accuracy of serum NF-L and GFAP levels (ie the biomarkers) at different time points postinjury for predicting the severity of neurologic impairment at 6 months postinjury as either motor complete (AIS grade A/B) or motor incomplete (AIS grade C/D) a group of patients who suffer traumatic spinal fracture and/or dislocation of the spinal column but without neurologic injury will be enrolled as non-SCI spine trauma control participants.
Bevonási feltételek: Age ≥ 19 years; Blunt (non-penetrating) traumatic SCI; Baseline neurologic impairment deemed "complete" (AIS grade A) or "incomplete" (AIS grade B, C, or D) based on clinical history/examination and/or diagnostic imaging; Bony spinal level involvement between C0 and L1, inclusive; Ability to have initial blood sample drawn within 24 hours of injury; Treated either surgically or non-surgically; Ability to provide informed consent according to the IRB/EC defined and approved procedures; Age ≥ 19 years; Traumatic spinal fracture and/or dislocation between C0 and L1 (inclusive) without SCI; Treated either surgically or nonsurgically; Ability to have initial blood sample drawn within 24 hours of injury; Ability to provide informed consent according to the IRB/EC defined and approved procedures.
Kizáró feltételek: Previous SCI; Preexisting thromboembolic disease or coagulopathy (disorders related to blood clotting), such as hemophilia or von Willebrand disease; Patients who in the investigator's opinion will not be compliant with the study procedures and patients who have any other conditions/injuries that in the investigator's opinion would render the study procedures dangerous; Penetrating SCI (eg, gunshot, stab); Isolated spinal injury below L1; Isolated radiculopathy without fracture; Isolated cauda equina injury; Patients with known diagnosis of multiple sclerosis.