Sickle Cell, Pain and Mediterranean Diet

Korábbi kezelés

• Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks)
• Currently receiving dialysis treatment

Más betegség

• History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome)
• History of Clostridium difficile infection in the preceding 12 weeks;
• Currently following a Mediterranean diet, vegan diet, or dietary restrictions (e.g., religious, food intolerance/allergy) that preclude adoption of a Mediterranean diet

Egyéb

• Unable to agree to maintain physical activity at the current level for the duration of the study
• Lack of access to a space to safely store and reheat food items
• Living in a facility that provides meals.
• Pregnancy or breastfeeding
• More than 7 in-patient hospital stays in the last year

• Sickle Cell Disease Diagnosis
• Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for > 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?")
• Ability to speak, read, write, and understand English
• A Mediterranean Eating Pattern for Americans (MEPA-III) score <13, indicating that they do not follow a Mediterranean diet.