Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults with peripheral arterial disease (narrowed arteries) in the legs. It compares different ways of measuring stress.

Életkor

18 Years and older

Nem

All sexes

A betegség stádiuma

Lower extremity PAD. The diagnosis must be shown by one of these: limb or aorta-femoral bypass surgery; angioplasty (opening arteries with a balloon) of the iliac or infrainguinal arteries; limb or foot amputation for artery disease; or leg pain when walking (intermittent claudication) plus one or more of these: an ankle brachial index (ABI) of less than 0.90, artery narrowing of ≥50% seen on angiography or duplex ultrasound, carotid revascularization, or carotid artery narrowing of at least 50% without symptoms.

Korábbi kezelés

People taking antiarrhythmic drugs class I or III cannot join.

A részvétel fő kizáró okai

• Atrial fibrillation
• Many extra heartbeats from the lower heart chambers (high premature ventricular contractions burden)
• Pacemaker with constant ventricular pacing
• Taking antiarrhythmic drugs class I or III

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Patients with peripheral arterial disease are at increased risk suffering from major adverse cardiac and limb events. Acute and chronic stress affect the cardiovascular system. Long-term negative stressors lead to cardiovascular diseases and can aggravate already existing cardiovascular diseases. However, current guidelines on cardiovascular disease prevention highlight stress as a cardiovascular risk factor there is a lack of consensus about the definition and measurement of stress. The aim of the proposed trial is to evaluate different stress measuring methods in patients with PAD depending on the occurrence of cardiovascular events.

A vizsgálat csoportja

• Patients with peripheral arterial disease.

  No control group is planned for this trial.