Mapping Stress and Pain Interactions (G072323N)

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults with fibromyalgia, chronic low back pain or recent (subacute) low back pain, and pain-free people as a comparison group. It studies how the body's stress systems relate to pain.

Életkor

18 to 55 years

Nem

All sexes

A betegség stádiuma

Fibromyalgia with widespread long-lasting pain confirmed by a specialist doctor, or non-specific low back pain that started 6 months ago or more, or less than 3 months ago. People with pain need an average pain score of at least 2/10 and a disability score of at least 14/70. Pain-free people can join as a comparison group. They must have no current pain and no long-lasting pain condition in the past. They must not have sought treatment for pain in the last 6 months. All need a BMI between 17 and 35 kg/m² and must speak Dutch well.

Korábbi kezelés

Any medicine must have been stable for at least 1 month before testing. No hormone replacement therapy. No past spinal surgery.

A részvétel fő kizáró okai

• Body weight >150 kg (331 lb), or anything that rules out MRI, like a pacemaker, metal in the body or fear of small spaces
• Being past menopause, pregnant now or in the past year, or breastfeeding
• Severe mental, brain or nerve, hormonal or heart and blood vessel conditions, now or in the past
• Past spinal surgery or injury, severe spine deformity, or back pain caused by nerve problems
• Regular drug use (≥1 time per week) or a severe communication or thinking disorder

A regiszter feltételei, szó szerint

Nézd meg, megfelelhetsz-e

Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.

• 18 és 55 év között vagy?IgenNem

Mit akar kideríteni a vizsgálat

The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary musculoskeletal (MSK) pain and a pain-free control group.

A vizsgálat 4 csoportja

• fibromyalgia

  Proof of a primary fibromyalgia diagnosis with chronic widespread pain by a specialist-doctor, with an average pain intensity of ≥2/10 on a Visual Analogue Scale, and with pain-related disability indicated by a score of ≥14/70 on the Pain Disability Index.

• chronic low back pain

  Chronic primary (non-specific) low back pain with primary onset ≥6 months ago, with an average pain intensity of ≥2/10 on a Visual Analogue Scale, and with pain-related disability indicated by a score of ≥14/70 on the Pain Disability Index.

• subacute low back pain

  Non-specific low back pain with primary onset \<3 months ago, with an average pain intensity of ≥2/10 on a Visual Analogue Scale, and with pain-related disability indicated by a score of ≥14/70 on the Pain Disability Index.

• pain-free/healthy control

  Exclusion criteria include current pain (\>0 on a Visual Analogue Scale); a pain condition in the last 6 months for which treatment was sought; history of a chronic pain syndrome.