Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation

Ki vehet részt

• outpatients
• ages 13 - 17 years
• meets current DSM-5 criteria for Obsessive Compulsive Disorder with screening CY-BOCS II score > 16 (moderate to severe)
• stable on chronic psychotropic medications and/or therapy for 8 weeks prior to the study and agreeable to continue throughout the study without changes
• participants may continue to take medications and record daily usage throughout the study
• capacity to provide informed assent and parent or legal guardian able to provide consent
• ability to tolerate clinical study procedures
• successfully complete the screening forms without any contraindications

Ki nem vehet részt

• Psychiatric: history of schizophrenia, bipolar disorder, substance/alcohol abuse disorder, current elevated suicide risk, prior psychosurgery, prior ECT
• Current and anticipated continued treatment with excluded medication (See prohibited list)
• Neurologic: severe neurocognitive disorder, seizure disorder, certain structural brain lesions (e.g., intracranial mass lesions, hydrocephalus, sequelae of meningitis, frank brain injury)
• TMS contraindications: implanted device; presence of metal in the head, including eyes and ears (excluding dental implants); certain tics; medications or systemic illness that predispose seizure risk; family history of 1st degree relative with seizure disorder
• Subjects with an unstable physical, systemic, or metabolic disorder (e.g., unstable hypertension, malnutrition secondary to eating disorder)
• Females who are pregnant or nursing (as determined by a questionnaire and pregnancy test)
• Inability to complete the research protocol as determined by the Principal Investigator