Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery

Ki vehet részt

• age ≥18 years
• Clinical diagnosis of acute ischemic stroke with internal carotid artery occlusion confirmed by imaging (CTA/MRA/DSA), including isolated intracranial internal carotid artery (I-type), internal carotid artery intracranial segment involving middle cerebral artery (L-type), or internal carotid artery intracranial segment involving middle and anterior cerebral arteries (T-type) (including tandem embolic occlusions of the internal carotid artery C1 or common carotid artery)
• Baseline NIHSS≥6, and meeting local guidelines for mechanical thrombectomy
• Time from onset or last known normal to randomization within 24 hours and proceeding to mechanical thrombectomy
• Signed informed consent (or by legal representative)

Ki nem vehet részt

• Prior stent implantation in the target vessel that would impede the use or removal of mechanical thrombectomy devices
• Pre-stroke mRS score >2
• Intracranial hemorrhage shown on imaging
• Subjects allergic to contrast agents
• Known or suspected internal carotid artery occlusion caused by dissection or atherosclerosis
• Vascular tortuosity preventing the use of balloon guide catheter
• Any other circumstances impeding mechanical thrombectomy implementation
• Acute occlusion of multiple vascular territories in bilateral anterior circulation or in both the anterior and posterior circulations confirmed by CTA/MRA
• Pregnant subjects
• Subjects refusing to cooperate or unable to tolerate interventional procedures
• Subjects whose expected lifetime are less than 90 days
• Midline shift or herniation with ventricular mass effect
• Subjects deemed unable to participate in follow-up by investigators
• Other situations deemed unsuitable for balloon guide catheter use by investigators