Endothelial Dysfunction After SCI
A legfontosabb adatok
- Hol
- Englewood (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- Craig HospitalEnglewood, Egyesült ÁllamokContact: Genevieve Madera, B.S.Résztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Craig Hospital
- Azonosító
- NCT07227727
- A regiszteradat frissítve
- 2025. november 14.
- Eredeti leírás
This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.A teljes eredeti leírásKevesebb
Endothelial Dysfunction After SCI: Mechanism and Therapeutic Target for SCI-related Cardiovascular Disease
This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.
Kizáró feltételek: Recent (< 3 months) surgery; Currently taking cardiovascular (statins, beta-blockers) therapeutics and/or other medications that could influence the outcome measures; Overt chronic diseases as assessed by: a) clinically documented medical history; b) physical examination; c) blood pressure and ECG at rest; and d) complete blood chemistries and hematological evaluation; Active infection; History of drug abuse; Current smoking history (within past 12 months); Report more than low-risk alcohol consumption.
SCI Inclusion Criteria; Over age 18 years; Chronic (>12 months) SCI; Motor complete (AIS A/B) SCI; Paraplegia (neurological level of injury [NLI] at T2 or below); Non-injured Inclusion Criteria; Over age 18 years.