Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children

Ki vehet részt

• Meeting any of the following conditions, and being unsuitable for standard end-to-end tracheal anastomosis or lacking sufficient native tracheal tissue for defect reconstruction:
• Congenital tracheal malformations: including congenital tracheomalacia, congenital tracheobronchial anomalies, complete tracheal rings, etc., with severe clinical respiratory symptoms and recommended for treatment after evaluation
• Acquired tracheal stenosis: including tracheal narrowing caused by disease, endotracheal intubation, or postoperative scar formation, with severe clinical respiratory symptoms and recommended for treatment after evaluation
• Tracheal injury or tissue loss due to trauma or burns requiring surgical repair
• Tracheal tumors: reconstruction of tracheal tissue after resection of benign or malignant tumors
• The term "severe clinical respiratory symptoms" includes:; Dependence on mechanical ventilation for more than 1 month due to airway narrowing or defect, with inability to wean; Airway stenosis exceeding 50% (confirmed by bronchoscopy or CT imaging), accompanied by persistent stridor, inspiratory dyspnea, or suprasternal/substernal retractions, causing impairment of daily activities or feeding difficulties; Unilateral or bilateral lung atelectasis persisting for more than 1 month due to tracheal or bronchial stenosis, with no sign of recovery; Recurrent post-obstructive pneumonia (≥3 episodes) in one or both lungs caused by tracheal or bronchial stenosis, requiring hospitalization for treatment

Ki nem vehet részt

• Malignant solid tumors with distant metastases that cannot be completely resected surgically or controlled with medication
• Presence of severe immunodeficiency (e.g., congenital immunodeficiency, HIV infection, ongoing chemotherapy, or recovery period after bone marrow transplantation)
• Presence of major congenital diseases or chromosomal abnormalities (e.g., Trisomy 13, Trisomy 18) with extremely poor prognosis as assessed clinically
• End-stage organ failure (e.g., persistent multiple organ failure, irreversible cardiopulmonary failure, or brain death)
• Inability to obtain legal informed consent from the lawful guardian
• Locally invasive tracheal tumors that cannot be completely resected surgically