Acute Exercise Responses With Blood Flow Restriction Under Dynamic Pressure Compared to Fixed Pressure in Patients With Severe Gonarthrosis
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- 50 és 85 év között vagy?
Forrás: NCT07316933: ki vehet részt
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Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- University of Valencia
- Azonosító
- NCT07316933
- A regiszteradat frissítve
- 2026. június 10.
- Eredeti leírás
This study aims to evaluate the acute effects of blood flow restriction (BFR) training on hypoalgesia and neuromuscular responses in patients with severe gonarthrosis by comparing the application of pressure with a dynamic versus a fixed configuration. There will be six different training conditions with varying levels of blood flow occlusion (%BFR) and percentage of load (%RM): 1) 30% RM and 50% BFR with dynamic pressure; 2) 30% RM and 50% BFR with fixed pressure; 3) 50% RM and 50% BFR with dynamic pressure; 4) 50% RM and 50% BFR with fixed pressure; 5) 30% RM and 80% BFR with dynamic pressure; 6) 30% RM and 80% BFR with fixed pressure.A teljes eredeti leírásKevesebb
Acute Responses to Different Blood Flow Restriction Exercise Configurations With Dynamic Pressure Compared to Fixed Pressure in Patients With Severe Gonarthrosis
This study aims to evaluate the acute effects of blood flow restriction (BFR) training on hypoalgesia and neuromuscular responses in patients with severe gonarthrosis by comparing the application of pressure with a dynamic versus a fixed configuration. There will be six different training conditions with varying levels of blood flow occlusion (%BFR) and percentage of load (%RM): 1) 30% RM and 50% BFR with dynamic pressure; 2) 30% RM and 50% BFR with fixed pressure; 3) 50% RM and 50% BFR with dynamic pressure; 4) 50% RM and 50% BFR with fixed pressure; 5) 30% RM and 80% BFR with dynamic pressure; 6) 30% RM and 80% BFR with fixed pressure.
Each participant will complete six individual sessions under different training conditions, assigned in a random order with a 72-hour interval between each session.
Bevonási feltételek: Age between 50 and 85 years; Diagnosis of severe gonarthrosis according to the clinical and radiographic criteria of the American College of Rheumatology guidelines; On the waiting list for unilateral total knee replacement (TKR) surgery.
Kizáró feltételek: Previous hip or knee replacement surgery and osteotomy within the last year; Participation in exercise programs (>2 days/week with training at intensities of 10-15 1RM) in the previous six months; Autoimmune arthritis; Medical conditions that contraindicate exercise; History of stroke, brain surgery, major depression, or self-reported cognitive impairment that could affect performance in the study; Cardiovascular, thrombotic, or vascular risk factors (uncontrolled hypertension, peripheral arterial disease, history of deep vein thrombosis or pulmonary embolism, heart failure, severe varicose veins, or uncontrolled anticoagulant therapy); Skin or local alterations at the cuff application site (ulcers, open wounds, infections, lymphedema, or severe edema); Pain in the contralateral leg with an intensity ≥80/100 mm on the visual analog scale (VAS) during daily activities; Inability to communicate normally or with impaired communication skills.