Repeated CBD Administration and Cannabis Outcomes
A legfontosabb adatok
- Ki végzi
- Hannah Harris
- Hol
- Lexington (Egyesült Államok)A helyszín megnézése
- Azonosító
- Állapot
- Toboroz
- Fázis
- Korai 1. fázis
- Résztvevők
- 23 fő, tervezett
- Kezdés
- 2026. aug. 5.
- Várható befejezés
- 2029. dec. 1.
- A vizsgálat típusa
- Beavatkozással járó, 6 csoportAz egyik csoport placebót (hatóanyag nélküli szert) kap, összehasonlításként.
- A vizsgált kezelések
- Cannabidiol, Medium Dose
- Cannabidiol, Higher Dose
- Active Inhaled Cannabis
- Placebo Cannabidiol
- Placebo Inhaled Cannabis
- A regiszteradat frissítve
- 2026. augusztus 12.
Ki vehet részt
- Életkor
- 18 év – 55 év
- Nem
- Nők és férfiak
- Egészséges önkéntesek
- Részt vehetnek
A regiszter feltételei, szó szerint
Mind a 20 feltétel megnézéseKevesebb
Ki vehet részt
- English-speaking, literate adults,
- Male or female,
- Between the ages of 18-55,
- Body Mass Index from 18.5-32.0 kg/m2,
- Not currently seeking treatment for cannabis or drug use,
- Able to provide written informed consent and perform all study procedures,
- If female, a negative pregnancy test and use of an effective form of contraception during study participation (e.g., oral contraceptive, abstinence, barrier method),
- Negative urine drug test for drugs of abuse (other than cannabis) prior to every Laboratory Session, and
- Otherwise healthy as determined by the investigator based on medical history, physical examination, vital signs, and laboratory chemistries
Ki nem vehet részt
- Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or alcohol that would require medical management,
- Currently using daily prescription medications to manage medical conditions or any drug that could interfere with the study, including potent CYP2C9, CYP3A4, or CYP2C19 inducers,
- Clinically significant acute medical problem (e.g., infection) or chronic medical problem requiring daily medication or ongoing medical care (e.g., hypertension, cardiovascular disease, diabetes, respiratory disorders [e.g., asthma, COPD]),
- Current or past history of major psychiatric disorder that would limit ability to participate in the study,
- History of seizure disorder,
- Clinically significant history of head injuries requiring medical management or long lasting sequalae, and
- Clinically significant abnormal laboratory findings,
- Use of cannabis exclusively for medical reasons (no recreational use reported),
- Current, unrelenting chronic pain that prevents participation (i.e., unable to sit in chair for 8 hours),
- Clinically significant abnormal ECG (as determined by study physician/cardiologist),
- Self-report of past 30-day use of synthetic cannabis (i.e., K2, Spice)
Nézd meg, megfelelhetsz-e
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 55 év között vagy?
Helyszínek itt: Egyesült Államok
- University of KentuckyLexington, Egyesült ÁllamokContact: Paul A Nuzzo, M.A.Résztvevőt keres
A vizsgálatról
Mit akar kideríteni a vizsgálat
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
A vizsgálat 6 csoportja
- Placebo CBD/Placebo Inhaled CannabisPlacebo, összehasonlításként
Participants will receive non-therapeutic, experimental doses of placebo/inactive cannabidiol in combination with non-therapeutic, placebo/inactive vaporized marijuana. Inactive cannabidiol and inactive marijuana will be administered once per session. It is possible to receive both inactive drugs on the same day. Inactive/Placebo Cannabidiol: Placebo/inactive cannabidiol will be administered orally. Inactive/Placebo: Experimental, non-therapeutic administration of an inactive/placebo marijuana dose will be administered through a vaporizer.
Kezelés: Placebo Cannabidiol és Placebo Inhaled Cannabis
- Placebo CBD/Active Inhaled CannabisA vizsgált kezelés
Participants will receive a non-therapeutic, experimental dose of inactive/placebo cannabidiol in combination with non-therapeutic, active vaporized marijuana. It is possible to receive inactive cannabidiol and active marijuana on the same day. Inactive/Placebo Cannabidiol: Active cannabidiol will be administered orally. Active Marijuana: Experimental, non-therapeutic administration of an active marijuana dose will be administered through a vaporizer.
Kezelés: Active Inhaled Cannabis és Placebo Cannabidiol
- CBD (Medium Dose)/Placebo Inhaled CannabisA vizsgált kezelés
Participants will receive a non-therapeutic, experimental dose of active cannabidiol in combination with non-therapeutic, inactive vaporized marijuana. It is possible to receive active cannabidiol, and inactive marijuana on the same day. Active Cannabidiol: Active cannabidiol will be administered orally. Inactive/Placebo Marijuana: Experimental, non-therapeutic administration of an inactive/placebo marijuana dose will be administered through a vaporizer.
Kezelés: Cannabidiol, Medium Dose és Placebo Inhaled Cannabis
- CBD (Medium Dose)/Active Inhaled CannabisA vizsgált kezelés
Participants will receive non-therapeutic, experimental doses of active cannabidiol in combination with non-therapeutic, experimental doses of active vaporized marijuana. Cannabidiol and marijuana doses will be administered once during each session. It is possible to receive both active drugs on the same day. Vaporized Marijuana: Active Marijuana administered through a vaporizer Cannabidiol: Active cannabidiol will be administered orally
Kezelés: Cannabidiol, Medium Dose és Active Inhaled Cannabis
- CBD (Higher Dose)/Placebo Inhaled CannabisA vizsgált kezelés
Participants will receive a non-therapeutic, experimental dose of active cannabidiol in combination with non-therapeutic, inactive vaporized marijuana. It is possible to receive active cannabidiol, and inactive marijuana on the same day. Active Cannabidiol: Active cannabidiol will be administered orally. Inactive/Placebo Marijuana: Experimental, non-therapeutic administration of an inactive/placebo marijuana dose will be administered through a vaporizer.
Kezelés: Cannabidiol, Higher Dose és Placebo Inhaled Cannabis
- CBD (Higher Dose)/Active Inhaled CannabisA vizsgált kezelés
Participants will receive non-therapeutic, experimental doses of active cannabidiol in combination with a non-therapeutic, experimental dose of active vaporized marijuana. Active cannabidiol and marijuana doses will be administered once during each session. It is possible to receive both active drugs on the same day. Active Cannabidiol: Active cannabidiol will be administered orally. Active Marijuana: Active Marijuana will be administered through a vaporizer.
Kezelés: Cannabidiol, Higher Dose és Active Inhaled Cannabis
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakAdatok és források
- Regiszteradat
- Szerepel a ClinicalTrials.gov-on.
- Hivatalos cím
- The Effects of Repeated CBD Administration on Cannabis Abuse Liability and Analgesia: A Human Laboratory Study
- Illeszkedési kérdések
- Forrás: NCT07434895: ki vehet részt
- A regiszteradat frissítve
- 2026. augusztus 12.