Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas

Ki vehet részt

• Patients 18 to 75 years of age with biochemically proven CD, Acromegaly, or tumor hyperprolactinemia as per current Endocrinology guidelines
• Clinical DCE-MRI protocol that is negative or equivocal for identifiable tumor
• Patient willing to have surgery if lesion found, or already scheduled for surgery and lesion identification would be helpful
• Able to provide informed consent and be capable of completing the imaging protocols
• Female subjects of childbearing potential (women of childbearing potential [WOCBP]) must have a negative urine pregnancy test ≤48 hours prior to the 18F-FET injection

Ki nem vehet részt

• Patients with known allergies to contrast agents or other imaging-related materials
• Patients with severe medical conditions that preclude participation in the study (e.g. inability to lie supine for 30-60 minutes)
• Patients with contraindications to MRI or PET scans
• Patients with successful MRI localization of the adenoma