IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success
A legfontosabb adatok
- Hol
- Los Angeles (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- University of California, Los AngelesLos Angeles, Egyesült ÁllamokContact: Rayne ShepardRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Lucas R. Cusumano, MD
- Azonosító
- NCT07494838
- A regiszteradat frissítve
- 2026. november 12.
- Eredeti leírás
Several clinical trials on genicular artery embolization (GAE) show significant clinical benefit for the majority of patients. However, a proportion of patients do not benefit from GAE, and responses vary across individual patients. Changes in metabolic activity on non-invasive imaging may correlate with improvement in symptoms of knee osteoarthritis. This study will assess changes in metabolic uptake on a hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) system in subjects undergoing GAE.A teljes eredeti leírásKevesebb
Several clinical trials on genicular artery embolization (GAE) show significant clinical benefit for the majority of patients. However, a proportion of patients do not benefit from GAE, and responses vary across individual patients. Changes in metabolic activity on non-invasive imaging may correlate with improvement in symptoms of knee osteoarthritis. This study will assess changes in metabolic uptake on a hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) system in subjects undergoing GAE.
Bevonási feltételek: Provided informed consent; Age ≥ 40 years; Ineligibility for or refusal of surgical management; Moderate-severe knee pain as determined by visual analog scale > 5 out of 10; Osteoarthritis based on X-ray. Kellgren-Lawrence score > 2 based on radiograph completed within 3 months of procedure date; Resistant/failed some form of conservative treatment (e.g. NSAIDS/physical therapy/steroid joint injection/hyaluronic acid joint injection) for at least 3 months; Able to comply with all treatments and protocol follow-up visits.
Kizáró feltételek: Prior total or partial knee replacement in the subject knee; Presence of pacemakers, aneurysm clips, neurostimulators, or any other metal implant not compatible with PET/MRI; History of fibromyalgia, autoimmune, or inflammatory disorder; History of any lumbar spine surgery, spine injections, or radicular pain in the extremity believed to originate from the spine; Allergy to iodinated contrast agents; Active infection or malignancy; Uncorrectable bleeding diathesis; Mild knee pain as determined by visual analog scale < 5 out of 10; OA on knee radiograph resulting in greater than 20 degree varus or valgus angulation; Moderate loss of kidney function, define as estimated glomerular filtration rate of less than 45 mL/min; Significant arterial atherosclerosis that would limit selective angiography; Recent (within 12 months) or active cigarette use; Active pregnancy.