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Résztvevőt keres itt: ChileFázis nélkül

Dual Tasking Training to Enhance Self-Efficacy in Individuals With Parkinson's Disease

A legfontosabb adatok

Ki végzi
Alvaro Reyes
Hol
Santiago (Chile)A helyszín megnézése
Azonosító
Állapot
Toboroz
Résztvevők
112 fő, tervezett
Kezdés
2026. okt. 5.
Várható befejezés
2029. jan. 31.
A vizsgálat típusa
Beavatkozással járó, 8 csoport
A vizsgált kezelések
  • dual tasking training
A regiszteradat frissítve
2026. október 30.

Ki vehet részt

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

A vizsgálat olyan felnőtteket keres, akiknek neurológus által megerősített idiopátiás Parkinson-kórjuk van, és önállóan tudnak járni. A gyakorlás során két feladatot végeznek egyszerre.

Életkor
18 éves vagy idősebb
Nem
Nők és férfiak egyaránt részt vehetnek.
A betegség stádiuma
Hoehn–Yahr I., II. vagy III. stádium. Nincs, enyhe vagy közepes kognitív zavar. Depressziós tünetekkel vagy anélkül.
Korábbi kezelés
A gyógyszer adagjának és típusának változatlannak kell lennie a vizsgálat kezdete előtti 3 hónapban.

A részvétel fő kizáró okai

  • Bármilyen más idegrendszeri vagy mozgásszervi betegség
  • Korábbi láb- vagy agysérülés, illetve műtét
  • Látás- vagy halláproblémák, amelyek befolyásolhatják a kognitív teszteket
  • Orvos által megállapított súlyos neurokognitív zavar

A regiszter feltételei, szó szerint

Mind a 11 feltétel megnézéseKevesebb

Ki nem vehet részt

  • The presence of any other concomitant neurological, musculoskeletal disease
  • History of leg or brain trauma or surgery
  • Clinical diagnosis of major neurocognitive disorder
  • Vision or hearing problems that may affect the performance of cognitive tests

Egyéb feltételek

  • Participants diagnosed with idiopathic Parkinson's disease confirmed by a neurologist will be recruited in this study. Inclusion criteria will be:
  • Hoehn \& Yahr stages I, II or III
  • Participants with no or mild to moderate neurocognitive impairments
  • Participants with and without symptoms of depression
  • Able to walk independently
  • Unaltered dose and type of medication up to three months before the commencement of the study
  • Participants able to understand and respond to the instructions given in the study

Helyszínek itt: Chile

  • Facultad de Ciencias de la RehabilitacionSantiago, ChileContact: Alvaro Reyes Principal Investigator, PhDRésztvevőt keres

A vizsgálatról

Mit akar kideríteni a vizsgálat

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and cognitive impairments that substantially reduce functional independence, social participation, and quality of life. A key psychosocial factor affected by these impairments is self-efficacy, defined as an individual's belief in their ability to successfully perform tasks and achieve personal goals. In people with PD, reduced self-efficacy is closely associated with motor dysfunction, cognitive decline, fear of falling, depressive symptoms, and decreased motivation for physical and social activities. These factors interact in a bidirectional manner, creating a negative cycle in which poor confidence limits participation, further accelerating functional deterioration.

A teljes eredeti leírásKevesebb

From a neurophysiological perspective, the degeneration of dopaminergic neurons in PD disrupts the automatic control of movement. As a consequence, individuals with PD rely more heavily on cognitive and attentional resources to execute daily motor activities. This reliance becomes particularly problematic in dual-tasking situations, where two tasks must be performed simultaneously, such as a motor task combined with a cognitive task or two concurrent motor tasks. Because attentional capacity is limited, dividing attention across tasks frequently results in performance declines in one or both tasks, a phenomenon referred to as dual-task interference or dual-task cost. Low confidence when facing these situations may reinforce avoidance behaviors, thereby further diminishing physical activity and community engagement.

Dual-task training has been proposed as a rehabilitation strategy to improve functional performance, self-efficacy, and daily functioning in people with PD. However, important gaps remain in the evidence. It is currently unclear whether motor-cognitive or motor-motor dual-task training is more effective, particularly when considering the presence or absence of cognitive impairment. Additionally, the relative impact of secondary cognitive versus secondary motor tasks on primary motor task performance has not been well established. Another unresolved issue concerns attentional prioritization strategies during dual-task training. Fixed-priority strategies require individuals to attend equally to both tasks, whereas variable-priority strategies involve alternating attention between tasks. The optimal strategy for individuals with PD, especially those with cognitive deficits, remains unknown.

The proposed research aims to address these knowledge gaps by systematically evaluating the effects of different dual-task training modalities and attentional prioritization strategies on self-efficacy, functional performance, and quality of life in individuals with PD, both with and without cognitive impairment. An additional objective is to investigate whether improvements in dual-task performance are associated with reduced attentional demands, as reflected by decreased activity in the prefrontal cortex, which is considered a key neural marker of cognitive load during task performance.

The research program comprises two complementary studies. Study 1 is a randomized clinical trial with a factorial design stratified by cognitive status. Participants with PD will be randomly assigned to one of four intervention groups combining dual-task modality (motor-cognitive or motor-motor) with attentional strategy (fixed-priority or variable-priority). All participants will undergo baseline assessments conducted by an interdisciplinary team of researchers. Baseline assessments include sociodemographic (age, gender, educational level, occupation), physical (weight, height) and clinical (stage of the disease, motor subtype, medication and cognitive screening measured with the Montreal cognitive assessment). Participants will complete 24 individualised training sessions over an eight-week period. Outcome measures include self-efficacy, motor and cognitive performance, quality of life, dual-task cost, and prefrontal cortex activity. Study 2 uses a cross-sectional design that includes individuals with PD from study 1 and a matched group of healthy older adults. Using identical assessment procedures, this study compares dual-task interference and prefrontal cortex activity between people with PD and healthy controls, providing additional insight into disease-specific cognitive-motor interactions. Overall, this research seeks to inform evidence-based, personalized rehabilitation strategies by identifying the most effective dual-task training approaches for improving confidence, functional ability, and quality of life in individuals with PD.

A vizsgálat 8 csoportja

  • No cognitive impairment, motor cognitive training, fixed priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and no cognitive impairments will perform motor cognitive training and will be instructed to focus attention on both tasks (motor and cognitive) through the entire session.

    Kezelés: dual tasking training

  • No cognitive impairment, motor cognitive training, variable priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and no cognitive impairments will perform motor cognitive training and will be instructed to focus attention on the motor tasks during half of the training session and on the secondary cognitive task during the second half of the training session.

    Kezelés: dual tasking training

  • No cognitive impairment, motor dual task training, fixed priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and no cognitive impairments will perform motor dual task training (two motor tasks) and will be instructed to focus attention on both motor tasks through the entire session.

    Kezelés: dual tasking training

  • No cognitive impairment, motor dual task training, variable priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and no cognitive impairments will perform motor dual task training (two motor tasks) and will be instructed to focus attention on the first motor task during half of the training session and on the secondary motor task during the second half of the training session.

    Kezelés: dual tasking training

  • Cognitive impairment, motor cognitive training, fixed priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and cognitive impairments will perform motor cognitive training and will be instructed to focus attention on both tasks (motor and cognitive) through the entire session.

    Kezelés: dual tasking training

  • Cognitive impairment, motor cognitive training, variable priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and cognitive impairments will perform motor cognitive training and will be instructed to focus attention on the first motor tasks during half of the training session and on the secondary cognitive task during the second half of the training session.

    Kezelés: dual tasking training

  • Cognitive impairment, motor dual task training, fixed priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and cognitive impairments will perform motor dual task training (two motor tasks) and will be instructed to focus attention on both motor tasks through the entire session.

    Kezelés: dual tasking training

  • Cognitive impairment, motor dual task training, variable priority instructionsA vizsgált kezelés

    In this group, participants with Parkinson's disease and cognitive impairments will perform motor dual task training (two motor tasks) and will be instructed to focus attention on the first motor task during half of the training session and on the secondary motor task during the second half of the training session.

    Kezelés: dual tasking training

Kérdések a vizsgálat csapatának

  1. Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
  2. Megtérítik az utazási költséget?
  3. Megtarthatom a saját orvosomat?
  4. Mi történik, ha ki akarok lépni?

Contact the study team: see the registry record → Contacts and Locations

Oldal nyomtatása az orvosomnak

Adatok és források

Regiszteradat
Szerepel a ClinicalTrials.gov-on.
Hivatalos cím
Enhancing Self-Efficacy in Individuals With Parkinson's Disease Through Dual Task Training: Effects of Task Modality, Attentional Prioritization, and Cognitive Status
MI-összefoglaló
A vizsgálat saját részvételi feltételeiből. Gépi kiolvasás: 2026. november 12.
A regiszteradat frissítve
2026. október 30.