Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease
A legfontosabb adatok
- Hol
- Boston és Salem (Egyesült Államok)Mind a 2 helyszín megnézése
Helyszínek itt: Egyesült Államok
- Massachusetts General HospitalBoston, Egyesült ÁllamokContact: Anahita Dua, MBCHB, MBA, MSCRésztvevőt keres
- Salem Hospital (Mass General Brigham)Salem, Egyesült ÁllamokContact: Shaidah Deghan, MD, MSCRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Massachusetts General Hospital
- Azonosító
- NCT07613840
- A regiszteradat frissítve
- 2026. szeptember 11.
- Eredeti leírás
The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peripheral artery disease (PAD) who have undergone a procedure to restore blood flow to their legs.A teljes eredeti leírásKevesebb
Personalizing Post Surgical Thromboprophylaxis for Patients With Peripheral Artery Disease
The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peripheral artery disease (PAD) who have undergone a procedure to restore blood flow to their legs.
The main questions it aims to answer are:
* Does the personalized plan lower the rate of blood clots in the treated leg one year after the procedure? * Does the personalized plan lower rates of amputation, repeat procedures, bleeding, and death compared to standard treatment?
Researchers will compare the personalized TARGET plan which uses a blood test to tailor each person's blood clot prevention medication to the standard treatment to see if the personalized approach works better.
Participants will:
* Be randomly assigned to either the personalized TARGET plan or standard treatment after their procedure * Have blood tests at 1 week and at 1, 3, 6, 9, and 12 months after their procedure * Have medications adjusted based on blood test results if assigned to the TARGET group
Bevonási feltételek: Patients with a named arterial extremity injury or named vessel revascularization for atherosclerosis requiring open and/or closed revascularization; Patients at the age of 18 or older.
Kizáró feltételek: Known pregnancy (females of childbearing potential will have a pregnancy test prior to surgery as per standard of care); Subject has severe hepatic impairment; Subject has a recent history of intracranial hemorrhage. If the patient has a history of cerebral hemorrhage with no new central nervous system disease of >1 year, the study team will consult with the; Patients who are younger than 18 years old; Prisoners, defined as those who have been directly admitted from a correctional facility; No atherosclerosis; Subject has active stomach ulcers.