Fermented Foods and Bowel Health in SCI
A legfontosabb adatok
- Hol
- Columbus (Egyesült Államok)A helyszín megnézése
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 70 év között vagy?
Forrás: NCT07640152: ki vehet részt
Helyszínek itt: Egyesült Államok
- Ohio State UniversityColumbus, Egyesült ÁllamokContact: Jia Li Li, PhDRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Ohio State University
- Azonosító
- NCT07640152
- A regiszteradat frissítve
- 2026. október 23.
- Eredeti leírás
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut health in adults with chronic spinal cord injury (SCI). The study will also evaluate the feasibility and tolerability of consuming fermented foods daily for 10 weeks. The main questions it aims to answer are:A teljes eredeti leírásKevesebb
High Fermented Food Intake to Improve Gut Microbiome and Bowel Dysfunction in Individuals With SCI
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut health in adults with chronic spinal cord injury (SCI). The study will also evaluate the feasibility and tolerability of consuming fermented foods daily for 10 weeks. The main questions it aims to answer are:
1. Does a high fermented food diet improve neurogenic bowel dysfunction symptoms and colonic transit in adults with SCI? 2. Does fermented food intake change gut microbiome composition, short-chain fatty acid production, and intestinal inflammation?
Researchers will compare a high fermented food diet to a control diet to evaluate effects on bowel health and gut microbiome outcomes.
Participants will:
* Consume study foods daily for 10 weeks * Attend 2 in-person study visits * Collect stool samples at home and ship them overnight to the research team using provided collection kits and prepaid shipping materials * Complete bowel health questionnaires and dietary recalls * Undergo Sitz marker testing with abdominal X-rays to assess colonic transit * Participate in biweekly monitoring contacts throughout the study period
Bevonási feltételek: Adults aged 18-70 years; At least 1 year post-onset of spinal cord injury, consistent with chronic spinal cord injury; Traumatic spinal cord injury involving cervical or thoracic levels; American Spinal Injury Association Impairment Scale classification A-D; Medically stable, with no recent hospitalizations or acute illnesses; Able to safely consume study foods, including fermented and control food products; Experiencing neurogenic bowel dysfunction, defined by at least one of the following:; Three or fewer bowel movements per week; More than 60 minutes required per bowel care routine; Symptoms of incomplete evacuation; Abdominal distension; Fecal incontinence; Established and stable bowel program, defined as a consistent individualized routine of timing, frequency, and evacuation methods that has remained unchanged for at least 4 weeks before enrollment.
Kizáró feltételek: Recent major bowel surgery within the past 12 weeks; Inability to safely undergo Sitz marker testing, including any of the following:; Inability to swallow the capsule; Pregnancy, due to radiation exposure; Contraindication to abdominal X-ray procedures; Active gastrointestinal disease, including Crohn's disease, ulcerative colitis, celiac disease, or gastrointestinal obstruction; Antibiotic use within the past 4 weeks; Current intake of probiotics or fermented foods exceeding 3 servings per day; Pregnancy or breastfeeding; Unresolved fecal impaction; Unstable bowel regimen that could interfere with accurate motility assessment.