Decision Aid for Anticoagulation Duration After Unprovoked Venous Thromboembolism

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults who had a first blood clot in a deep vein or lung with no clear or only a weak cause. They have taken blood thinners for at least 3 months and must decide whether to continue.

Életkor

18 years or older

Nem

All sexes

A betegség stádiuma

First confirmed clot in a large (proximal) deep leg vein and/or a segmental or larger lung clot (pulmonary embolism), with no clear or only a weak cause. Enrolment within 12 months of the diagnosis.

Korábbi kezelés

At least 3 months of full-dose blood thinner treatment, and still taking it now. No earlier dedicated visit to decide long-term blood thinner use.

A részvétel fő kizáró okai

• More than one clot with no clear or only a weak cause
• Clot caused by a strong trigger such as major surgery, major injury, a plaster cast or long bed rest, or a lasting trigger such as active cancer
• Women at very low risk of another clot (HERDOO2 score 0-1)
• High bleeding risk, so blood thinners should be stopped
• Need for long-term blood thinners for another reason, such as atrial fibrillation

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a common condition that is typically treated with blood thinners (anticoagulants). After completing at least 3 months of treatment for a first unprovoked or weakly provoked VTE, patients and clinicians must decide whether to stop anticoagulation or continue treatment for a longer period. Continuing anticoagulation reduces the risk of another blood clot but increases the risk of bleeding. Because both options involve important benefits and risks, this decision should reflect the patient's values and preferences.

A vizsgálat 2 csoportja

• Usual CareNincs vizsgálati kezelés, összehasonlításként

  Participants receive standard thrombosis clinic care and clinician-patient discussions regarding continuation versus discontinuation of anticoagulation following a first unprovoked or weakly provoked venous thromboembolism. No structured patient decision aid is used.

• DECIDE-VTE Patient Decision AidA vizsgált kezelés

  Participants receive the DECIDE-VTE Patient Decision Aid in addition to usual thrombosis clinic care. The decision aid provides evidence-based information regarding the risks and benefits of continuing versus discontinuing anticoagulation after a first unprovoked or weakly provoked venous thromboembolism and includes a structured values clarification exercise to support shared decision-making. Participants and clinicians make the final treatment decision together during the Decision Visit.