Holistic Healing for Knee Osteoarthritis

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults with early primary knee osteoarthritis and moderate to severe knee pain. It compares standard medical care, Ayurvedic care and a combination of both.

Életkor

30 to 65 years

Nem

Men and women can join.

A betegség stádiuma

Primary osteoarthritis in at least one knee, Kellgren-Lawrence grade 1 or 2 (mild to moderate). Pain score of 5 or more out of 10 at the start.

Korábbi kezelés

People who had total knee replacement surgery, recent corticosteroid use for knee problems, or earlier joint injections of viscosupplementation (gel injected into the knee) cannot join.

A részvétel fő kizáró okai

• Arthritis caused by a body-wide inflammatory joint disease, or knee osteoarthritis after an injury
• Allergy to the modern or Ayurvedic medicines used in the study
• Skin disease where a study treatment is applied
• Uncontrolled diabetes or chronic kidney failure
• Pregnant or breastfeeding women

A regiszter feltételei, szó szerint

Nézd meg, megfelelhetsz-e

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• 30 és 65 év között vagy?IgenNem

Mit akar kideríteni a vizsgálat

This study is a single-center, three-arm, open-label randomized controlled trial designed to compare the effectiveness of integrated care, standard medical care, and Ayurvedic care in adults with early knee osteoarthritis (Kellgren-Lawrence grades I-II). Knee osteoarthritis is a leading cause of pain, functional limitation, and reduced quality of life, and current management often provides incomplete symptom relief. Although conventional medical and Ayurvedic interventions are widely used in clinical practice, comparative evidence evaluating these treatment approaches individually and in combination remains limited.

A vizsgálat 3 csoportja

• Standard Medical CareMár használt kezelés, összehasonlításként

  Participants assigned to this arm will receive standard medical management for knee osteoarthritis for 24 weeks. Treatment includes oral paracetamol, topical diclofenac spray administered as required for pain relief, transcutaneous electrical nerve stimulation (TENS), and superficial heat or cold therapy. Participants will be assessed at baseline and followed at 4, 8, 12, 16, 20, and 24 weeks.

  Kezelés: Topical Diclofenac Spray, Portable TENS, Paracetamol és Superficial Heat or Cold Therapy

• Ayurvedic CareA vizsgált kezelés

  Participants assigned to this arm will receive oral Trayodashang Guggulu (1 g twice daily with lukewarm water), Ashwagandha Churna (3 g twice daily with lukewarm water), Janubasti administered according to the predefined schedule, and topical application of Mahanarayana Taila (10 mL per knee; total 20 mL per application) applied twice daily for 24 weeks. Janubasti will be administered in 21 sessions, with 7 sessions during Weeks 1-2, 7 sessions during Weeks 9-10, and 7 sessions during Weeks 17-18. Participants will undergo scheduled follow-up assessments throughout the study.

  Kezelés: Trayodashang Guggulu, Ashwagandha Churna, Janubasti és Mahanarayana Taila

• Integrated CareA vizsgált kezelés

  Participants assigned to this arm will receive oral Trayodashang Guggulu (1 g twice daily), Ashwagandha Churna (3 g twice daily), topical diclofenac spray as required, and portable transcutaneous electrical nerve stimulation (TENS) for 24 weeks. Participants will undergo scheduled follow-up assessments at Weeks 4, 8, 12, 16, 20, and 24.

  Kezelés: Trayodashang Guggulu, Ashwagandha Churna, Topical Diclofenac Spray, Portable TENS és Superficial Heat or Cold Therapy