Lemborexant on Perioperative Sleep Quality in Patients With Brain Tumor Undergoing Surgery
A legfontosabb adatok
- Fázis
- 2. fázis
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 65 év között vagy?
Forrás: NCT07903051: ki vehet részt
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Beijing Tiantan Hospital
- Azonosító
- NCT07903051
- A regiszteradat frissítve
- 2026. október 29.
- Eredeti leírás
This study tests whether lemborexant can improve perioperative sleep quality in people with brain tumor undergoing surgery. Adults with brain tumor scheduled for surgery may join. Participants will be randomly assigned to take lemborexant or a placebo the night before surgery. Researchers will measure sleep quality, anesthesia recovery, pain, postoperative recovery, and other outcomes.A teljes eredeti leírásKevesebb
Effect of Lemborexant on Perioperative Sleep Quality in Patients With Brain Tumor Undergoing Surgery: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial
This study tests whether lemborexant can improve perioperative sleep quality in people with brain tumor undergoing surgery. Adults with brain tumor scheduled for surgery may join. Participants will be randomly assigned to take lemborexant or a placebo the night before surgery. Researchers will measure sleep quality, anesthesia recovery, pain, postoperative recovery, and other outcomes.
Bevonási feltételek: Patients scheduled for elective craniotomy for brain tumor resection; Age 18-65 years; ASA physical status I-III; Preoperative sleep disturbance, defined as Pittsburgh Sleep Quality Index (PSQI) score > 5; Signed informed consent.
Kizáró feltételek: Chronic use of sedative-hypnotic medications; Use of systemic moderate or strong CYP3A inhibitors and/or inducers within 1 week before surgery; Active epilepsy or poorly controlled epilepsy; Acute psychiatric illness; Severe sleep apnea, COPD, severe daytime sleepiness (Epworth Sleepiness Scale [ESS] score ≥ 16), or history of narcolepsy and/or cataplexy; Severe hepatic or renal impairment; Any condition that, in the opinion of the principal investigator, precludes participation in the study; Tumor located in the brainstem, thalamus, Wernicke's area, Broca's area, or frontal pole; Severe neurological deficit with Karnofsky Performance Status (KPS) < 60.