Építés alatt – nem éles oldal
Belépés
Toborzás még nem indultFázis nélkül

EFFECT OF ADDING BLOOD FLOW RESTRICTION TRAINING TO CLOSED CHAIN EXERCISE IN KNEE OSTEOARTHRITIS

A legfontosabb adatok

Ki végzi
Rasha Abdel Kader Abdel Azeem Khtab
Hol
Egyiptom1 helyszín, 1 országbanVálassz országot a helyszínekhez
Azonosító
Állapot
Toborzás még nem indult
Résztvevők
60 fő, tervezett
Kezdés
2026. dec. 1.
Várható befejezés
2028. febr. 28.
A vizsgálat típusa
Beavatkozással járó, 2 csoportAz egyik csoport egy már használt kezelést kap, összehasonlításként.
A vizsgált kezelések
  • Traditional and Closed Kinetic Chain Exercise Program
A regiszteradat frissítve
2026. november 4.

Ki vehet részt

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for adults aged 40 to 60 with mild to moderate knee osteoarthritis and long-lasting knee pain. It tests adding blood flow restriction training to knee exercises.

Életkor
40 to 60 years
Nem
All sexes
A betegség stádiuma
Mild to moderate knee osteoarthritis (Kellgren-Lawrence grades II-III). Knee pain for at least three months, at least 3/10 on the VAS pain scale or an equivalent WOMAC pain score. Body mass index (BMI) from 25 to 29.9 kg/m². Must walk without help and be able to do the exercises.
Korábbi kezelés
No knee surgery in the previous 12 months.

A részvétel fő kizáró okai

  • Severe knee osteoarthritis (Kellgren-Lawrence grade IV)
  • Inflammatory joint disease, such as rheumatoid arthritis
  • Heart, blood vessel or nerve disorders that rule out blood flow restriction training
  • Taking part in another leg strengthening or blood flow restriction program during the study
  • Memory or thinking problems, or being unable to follow exercise instructions

A regiszter feltételei, szó szerint

Mind a 14 feltétel megnézéseKevesebb

Ki vehet részt

  • Participants diagnosed with mild to moderate knee osteoarthritis (Kellgren-Lawrence grades II-III)
  • Participants aged between 40 and 60 years
  • Body mass index (BMI) ranging from 25 to 29.9 kg/m²
  • Presence of chronic knee pain for at least three months
  • Pain intensity of ≥3/10 on the Visual Analog Scale (VAS) or equivalent WOMAC pain score
  • Ability to ambulate independently and perform closed kinetic chain exercises
  • Participants who are medically fit to participate in low-load resistance exercise with or without blood flow restriction training
  • Willingness to participate and provide written informed consent

Ki nem vehet részt

  • History of knee surgery within the previous 12 months
  • Diagnosis of inflammatory joint diseases, such as rheumatoid arthritis
  • Presence of cardiovascular, vascular, or neurological disorders that contraindicate blood flow restriction training
  • Cognitive impairment or inability to understand and follow exercise instructions
  • Presence of severe knee osteoarthritis (Kellgren-Lawrence grade IV)
  • Participation in any other structured lower limb strengthening or blood flow restriction training program during the study period

Nézd meg, megfelelhetsz-e

Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.

  • 40 és 60 év között vagy?

Ennek a vizsgálatnak nincs helyszíne itt: Egyesült Államok.

Egy országban van helyszíne. Válassz országot, hogy lásd a helyszíneket.

A vizsgálatról

Mit akar kideríteni a vizsgálat

Knee osteoarthritis is a common joint condition that causes knee pain, stiffness, muscle weakness, and difficulty performing daily activities such as walking, climbing stairs, and standing up from a chair. Exercise therapy is commonly used to improve muscle strength, reduce pain, and restore physical function. However, some patients may find traditional strengthening exercises difficult because of pain and increased stress on the knee joint.

A teljes eredeti leírásKevesebb

Blood flow restriction (BFR) training is a rehabilitation technique that uses a specialized cuff placed around the upper thigh to partially restrict blood flow during exercise. This technique may help improve muscle strength while using lighter exercise loads.

The purpose of this study is to investigate whether adding blood flow restriction training to traditional physical therapy and closed kinetic chain exercises provides additional benefits for patients with knee osteoarthritis.

This randomized controlled trial will include 60 male and female participants aged 40 to 60 years with mild to moderate knee osteoarthritis. Participants will be randomly assigned to one of two groups, with 30 participants in each group.

The first group will receive traditional physical therapy exercises combined with closed kinetic chain exercises, such as mini-squats, step-ups, step-downs, partial lunges, and wall slides.

The second group will receive the same exercise program with the addition of blood flow restriction training.

Both groups will participate in supervised treatment sessions twice weekly for eight weeks, for a total of 16 sessions.

The researchers will assess knee pain, knee range of motion, quadriceps muscle strength, knee function, mobility and fall risk, quality of life, and patient satisfaction. Assessments will be conducted before treatment, immediately after the eight-week intervention, and one month after completing treatment.

The study aims to determine whether adding blood flow restriction training to closed kinetic chain exercises can improve rehabilitation outcomes in individuals with knee osteoarthritis.

A vizsgálat 2 csoportja

  • Traditional Exercise and Closed Kinetic Chain ExercisesMár használt kezelés, összehasonlításként

    Participants in the control group will receive a traditional therapeutic exercise program combined with closed kinetic chain exercises, including seated knee extensions, hip adduction and abduction, straight leg raises, short-arc knee extensions, ankle pumps, hamstring curls, mini-squats, step-ups, step-downs, partial lunges, and wall slides. Treatment will be delivered twice weekly for eight weeks, for a total of 16 supervised sessions.

    Kezelés: Traditional and Closed Kinetic Chain Exercise Program

  • Blood Flow Restriction Training Combined with Closed Kinetic Chain ExercisesA vizsgált kezelés

    Participants in the experimental group will receive the same traditional therapeutic exercise and closed kinetic chain exercise program as the control group, with the addition of blood flow restriction training. Blood flow restriction will be applied using a pneumatic cuff positioned around the proximal thigh during low-load resistance or closed kinetic chain exercises. Treatment will be delivered twice weekly for eight weeks, for a total of 16 supervised sessions.

    Kezelés: Traditional and Closed Kinetic Chain Exercise Program

Kérdések a vizsgálat csapatának

  1. Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
  2. Megtérítik az utazási költséget?
  3. Megtarthatom a saját orvosomat?
  4. Mi történik, ha ki akarok lépni?

Contact the study team: see the registry record → Contacts and Locations

Oldal nyomtatása az orvosomnak

Adatok és források

Regiszteradat
Szerepel a ClinicalTrials.gov-on.
MI-összefoglaló
A vizsgálat saját részvételi feltételeiből. Gépi kiolvasás: 2026. november 14.
Illeszkedési kérdések
Forrás: NCT07917559: ki vehet részt
A regiszteradat frissítve
2026. november 4.