What researchers published on Familial hypercholesterolaemia
2,785 papers, newest first.
Showing 140 of 2,785
Not labelled yetRapid Screening and Etiological Stratification of Inherited Dyslipidemias by Infrared Microspectroscopy.Analytical chemistry
Not labelled yetSex-specific clinical and psychosocial characteristics among individuals with familial hypercholesterolemia reporting side-effects of lipid-lowering therapy.Atherosclerosis
Not labelled yetFamily planning, pregnancy and breastfeeding care in familial hypercholesterolaemia (Taking ACTion to Improve Care of coupleS in FH (TACTICS)): a mixed methods study.Atherosclerosis
Meta-analysisEffects of non-soy legume protein on lipid profile in hypercholesterolemic adults: a systematic review and meta-analysis of randomized controlled trials.BMC cardiovascular disorders
In plain wordsRead moreRead the paper on PubMedNot labelled yetA study protocol for developing an implementation strategy bundle to enhance adoption of pediatric familial hypercholesterolemia screening.Implementation science communications
Not labelled yetHigh Cholesterol Facilitates Ovarian Androgen Production and Contributes to the Development of Polycystic Ovary Syndrome.Phenomics (Cham, Switzerland)
Not labelled yetEvinacumab for children and adolescents with homozygous familial hypercholesterolemia: a plain language summary.Expert review of cardiovascular therapy
Not labelled yetPopulation-based screening for familial hypercholesterolaemia.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V
Not labelled yet[Hypercholesterolemia and lipid profile alterations in Moroccan patients with myocardial infarction: A case-control study].Annales de cardiologie et d'angeiologie
Not labelled yetTUDCA was identified as a potential therapeutic drug for nonalcoholic steatohepatitis complicated with hypercholesterolemia targeting ADRA2C by integrated bioinformatics and experimental verification.Biology direct
Not labelled yetWhat Is Familial Hypercholesterolemia?JAMA
Not labelled yetReproductive factors in women with familial hypercholesterolaemia.European journal of preventive cardiology
Not labelled yetAuthor Correction: In vivo base editing gene therapy for heterozygous familial hypercholesterolemia: a phase 1 trial.Nature medicine
Not labelled yetIn familial hypercholesterolaemia, remnant cholesterol above 1 mmol/L is associated with 50% higher risk of coronary artery disease.European journal of preventive cardiology
Not labelled yetNon-HDL cholesterol as a lipid control target in severe hypercholesterolemia in primary care: a sex-stratified analysis.Atherosclerosis
Not labelled yetTranslating the familial hypercholesterolemia pediatric diagnostic score (FH-PeDS) into clinical practice: Development of an open-access online tool.Journal of clinical lipidology
Not labelled yetFamilial Hypercholesterolemia Screening: From Pediatric Detection to Life-long Management.Journal of atherosclerosis and thrombosis
Not labelled yetComment on "Chronic kidney disease is associated with worse survival after revascularization in subjects with genetically diagnosed familial hypercholesterolemia and significant coronary artery disease".American heart journal plus : cardiology research and practice
Not labelled yetImpact of baseline LDL-C and Lp(a) levels on PCSK9-targeting therapy efficacy in subjects with familial hypercholesterolemia: real-world data from a tertiary lipid center.Nutrition, metabolism, and cardiovascular diseases : NMCD
Not labelled yetReducing LDL-Cholesterol Burden in Homozygous Familial Hypercholesterolemia: The Earlier, The Lower, The Longer, The Better.JACC. Case reports
Not labelled yetElevated YKL-40 and associations of inflammatory profiles with metabolic parameters in pediatric heterozygous familial hypercholesterolemia under pharmacological lipid-lowering therapy.Cytokine
ReviewImpact of Hypercholesterolemia on Pregnancy and Postpartum.Obstetrics and gynecology clinics of North America
Not labelled yetDiagnostic Yield and Clinical Phenotype in a Lithuanian Familial Hypercholesterolemia Cohort with Heterogeneous Sequencing Platforms.Medicina (Kaunas, Lithuania)
Not labelled yetSulforaphane Attenuates Antipsychotic-Elicited Hypercholesterolemia Through Inhibition of Pregnane X Receptor.Biomolecules
Not labelled yetPlasma Lipidomic Phenotype Associated with Pathogenic LDLR Variants in Familial Hypercholesterolemia.International journal of molecular sciences
Randomised trialEffects of a Chilean Hazelnut-Supplemented Diet on Oxidative Stress and Cytokine Expression in PBMCs of Hypercholesterolemic Adults: A Randomized Controlled Trial.Nutrients
In plain wordsRead moreRead the paper on PubMedNot labelled yetCoronary artery calcium scoring and coronary computed tomography angiography in familial hypercholesterolemia: current evidence and future directions.Current opinion in lipidology
Not labelled yetEstimated Small Dense LDL Cholesterol and Coronary Artery Disease in Familial Hypercholesterolemia.Journal of atherosclerosis and thrombosis
Systematic reviewEffectiveness and safety of atorvastatin/ ezetimibe fixed-dose combination in hypercholesterolemia: a systematic review and network meta-analysis.PeerJ
In plain wordsRead moreRead the paper on PubMedRandomised trialA randomized study comparing plant sterol- and soluble fiber-enriched soymilk with plain soymilk in adults with elevated LDL cholesterol.European journal of nutrition
In plain wordsRead moreRead the paper on PubMedNot labelled yetHealth-Related Quality of Life in Homozygous Familial Hypercholesterolemia: Results from an Online Survey.Patient preference and adherence
ReviewUsing Implementation Science to Improve Guidelines-Based Care to Lower Atherosclerosis Risk Due to Familial Hypercholesterolemia.Current atherosclerosis reports
Not labelled yetGinsenoside Rb3 Combined with 20(S)-Protopanaxadiol Ameliorates Hypercholesterolemia via the Regulation of Lipid Metabolism and Gut Microbiota.Journal of agricultural and food chemistry
Not labelled yetCardiovascular risk among individuals with and without a genetic mutation for familial hypercholesterolemia: A long-term study.Journal of clinical lipidology
Not labelled yetHeterozygous familial hypercholesterolemia in Italian children: a road map through a single center's experience.European journal of pediatrics
Not labelled yetHigh-intensity interval training and moderate-intensity continuous training versus usual care in adults with familial hypercholesterolaemia: protocol for the UPPA-FH three-arm randomised trial.BMJ open
Not labelled yetManaging Ketogenic Diet-Induced Hypercholesterolemia.Journal of the American College of Cardiology
Not labelled yetCorrigendum to "Optimizing treatment in homozygous familial hypercholesterolemia: Monocentric observational clinical study on efficacy and safety of evinacumab and lomitapide combination" [J Clin Lipidol 20 (2026) 1086-1096].Journal of clinical lipidology
Observational studyVascular risk factors after stroke in the older people: a population-based study.BMC geriatrics
Not labelled yetFamilial hypercholesterolaemia and thymic ageing in a Chinese cohort.European heart journal
Not labelled yetPolygenic risk score assessment of LDL-Cholesterol levels and progression to severe hypercholesterolemia and statin treatment; a longitudinal study from a large middle eastern biobank.American journal of preventive cardiology
Not labelled yetAge-stratified prevalence and associated risk factors of hypertension, diabetes and hypercholesterolemia in Nepal: Insights from the STEPS survey 2019.PloS one
Not labelled yetEffect of rosuvastatin and ezetimibe therapy on LDL-cholesterol reduction and non-invasive arterial injury markers in children with heterozygous familial hypercholesterolemia: a prospective, open-label, randomized study.Frontiers in cardiovascular medicine
Not labelled yetRETRACTED: Ardissino et al. Short-Term Effect of Nutraceutical Fruit Juices on Lipid Metabolism in Patients with Acquired Hypercholesterolemia. Int. J. Mol. Sci. 2023, 24, 7358.International journal of molecular sciences
Not labelled yetSignificant Associations of Achilles Tendon Thickness With Atherosclerotic Diseases and Atherosclerotic Risk Factors in Non-Familial Hypercholesterolemia Patients: A Cross-Sectional Study.Journal of clinical medicine research
Case reportFamilial hypercholesterolemia in pregnancy: A case of acute myocardial infarction treated with lipid apheresis.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Not labelled yetImplementing genetics-based cascade testing for familial hypercholesterolemia in Colombia: Results from a pilot study and implications for national screening strategies.Journal of clinical lipidology
Not labelled yetEbselen attenuates selected cardiac and vascular alterations in rats exposed to a cholesterol/cholic acid diet.Journal of molecular histology
Not labelled yetFunctional data for LDLR variant classification: comparative insights from high-content microscopy and flow cytometry assays.Atherosclerosis
Meta-analysisEfficacy and Safety of Enlicitide in Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Endocrinology, diabetes & metabolism
In plain wordsRead moreRead the paper on PubMedReviewEffectiveness of LDL Apheresis Techniques for Reducing LDL-C in Familial Hypercholesterolemia: A Systematic Review and Meta-Analysis.Health science reports
Not labelled yetOpaganib Protects Against High-Fat Diet-Induced Hypercholesterolemia and Liver Steatosis in Mice.Diabetes, metabolic syndrome and obesity : targets and therapy
Not labelled yetCorrigendum to "Ischemic stroke and intracranial large-artery disease risk in familial hypercholesterolemia: A prospective Japanese study" [Atherosclerosis, 415, (2026), 120674].Atherosclerosis
Not labelled yetResponse to the letter regarding the manuscript entitled: "Lipid-lowering therapy in patients with hypercholesterolemia in terms of the POLSCORE and SCORE2 scales. A single-center retrospective analysis".Cardiology journal
ReviewTowards a suitable biomarker for childhood screening for familial hypercholesterolemia: a systematic literature review.Clinical chemistry and laboratory medicine
PreprintDesigning to Implement Genomics Informed ASCVD Risk Assessment: Patient and Clinician Perspectives about Identifying and Managing the Underlying Causes of Severe Hypercholesterolemia.medRxiv : the preprint server for health sciences
Not labelled yetSafety and tolerability of nonstatin LDL-cholesterol-lowering therapies: A systematic review and pairwise meta-analysis of randomized controlled trials.Journal of clinical lipidology
Not labelled yetExpanding the LDL-C criterion for suspected homozygous familial hypercholesterolemia to include treated and imputed elevations.Journal of clinical lipidology
Not labelled yetUncovering dysbetalipoproteinemia in a patient initially diagnosed with familial hypercholesterolemia: The role of whole exome sequencing and longitudinal follow-up in diagnostic precision and care.Journal of clinical lipidology
Observational studyOptimizing treatment in homozygous familial hypercholesterolemia: Monocentric observational clinical study on efficacy and safety of evinacumab and lomitapide combination.Journal of clinical lipidology
Not labelled yetImplementation of an EHR-supported multidisciplinary lipid management program for suspected familial hypercholesterolemia: Early clinical and implementation outcomes.American journal of preventive cardiology
ReviewClinical considerations on the use of evinacumab for the treatment of homozygous familial hypercholesterolemia.American journal of preventive cardiology
Not labelled yetTreatment patterns in homozygous familial hypercholesterolemia: Undertreatment and delayed adoption of low-density lipoprotein receptor-independent therapies.American journal of preventive cardiology
Not labelled yetLevonorgestrel-ethinyl estradiol impairs hepatic lipid clearance to induce hypercholesterolemia via PCSK9-mediated LDLR and CD36 dysregulation.Toxicology and applied pharmacology
Not labelled yetReverse Cascade Genetic Screening for Revealing New Cases of Familial Hypercholesterolemia in Russia: Pilot Project.Frontiers in bioscience (Scholar edition)
ReviewFamilial Hypercholesterolemia in Latin America: Unmet Needs, Barriers, and Challenges.Journal of lipid and atherosclerosis
Not labelled yetCorrection to: Familial hypercholesterolaemia in children and adolescents: a European Atherosclerosis Society consensus statement.European heart journal
ReviewDiagnosis of familial hypercholesterolemia through population screening.Expert review of cardiovascular therapy
Randomised trialEffects of Protocatechuic Acid on Endothelial Function and HDL Functionality in Hypercholesterolemic Subjects: A Randomized Double-Blind Placebo-Controlled Trial.Nutrients
In plain wordsRead moreRead the paper on PubMedCase reportCombined heart and liver transplantation for homozygous familial hypercholesterolaemia: 35-year post-operative outcomes.Global cardiology science & practice
Not labelled yetMachine Learning Triage of LDLR Variants of Uncertain Significance Using Predictor Concordance and ACMG-Aligned Evidence Mapping.Genes
Not labelled yetPutative protective role of PCSK9 variants in a multigenerational family with familial hypercholesterolemia.Atherosclerosis plus
Not labelled yetReal-World Outcomes of Lipoprotein Apheresis in Homozygous Familial Hypercholesterolemia: A Single-Center Longitudinal Experience.Journal of clinical medicine
ReviewLerodalcibep-liga as an Injectable Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)-Targeted Therapy for Patients With Hypercholesterolemia.The Annals of pharmacotherapy
ReviewCurrent challenges in diagnosing homozygous familial hypercholesterolemia: Insights from the historical evolution of diagnostic criteria.Journal of clinical lipidology
Not labelled yetPrevalence and Impact of a Pathogenic CYP27A1 Variant on the Phenotypes Among Patients with Monogenic Heterozygous Familial Hypercholesterolemia.Internal medicine (Tokyo, Japan)
Not labelled yetSevere diet-induced hypercholesterolemia mimicking familial hypercholesterolemia in atypical lean mass hyper-responders on ketogenic diets: A case series.Journal of clinical lipidology
Not labelled yetGut Microbiota Mediates the Relationship Between Immune Cells and Familial Hypercholesterolemia: A Mendelian Randomization Study.Endocrine, metabolic & immune disorders drug targets
PreprintCholesterol-Mediated Modulation of Collecting Lymphatic Vessel Contractility: Exploring Cholesterol Depletion as a Therapeutic Alternative to Improve Lymphatic Function in Hypercholesterolemia.bioRxiv : the preprint server for biology
ReviewFamilial Hypercholesterolemia.Methodist DeBakey cardiovascular journal
Meta-analysisDiagnostic accuracy of peripheral ultrasound in familial hypercholesterolemia: a systematic review and meta-analysis.Scandinavian cardiovascular journal : SCJ
In plain wordsRead moreRead the paper on PubMedNot labelled yetTherapeutic inertia in children with heterozygous familial hypercholesterolemia: challenges of guideline-recommended goals.Expert review of cardiovascular therapy
Not labelled yetFamilial hypercholesterolemia cascade testing: Insights from the Dutch Program.Journal of clinical lipidology
Not labelled yetCurrent, novel and emerging lipid-lowering therapies in pediatric familial hypercholesterolemia.Current opinion in lipidology
Not labelled yetPredictors of aortic stenosis in homozygous familial hypercholesterolemia: A study from the Canadian HoFH registry.Journal of clinical lipidology
Not labelled yetCorrection to: Genetic screening of children for familial hypercholesterolaemia: the VRONI study.European heart journal
ReviewEmerging Nucleic Acid-Based Therapies for Hypercholesterolemia with Focus on a New Modality, Liver-Directed miR-30c Analog C2.Cells
Not labelled yetSex differences and gender-related factors in the management and perception of LDL-cholesterol in ASCVD: Real-Life evidence from the EPHESUS registry in cardiology practice.Atherosclerosis plus
Not labelled yetPotential Shared Immunometabolic Signatures Between Familial Hypercholesterolemia and Major Depressive Disorder: Integrative Transcriptomic Analysis, Mendelian Randomization, and Clinical Validation.International journal of molecular sciences
Case reportPhenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis.Molecular genetics & genomic medicine
Not labelled yetDetecting familial hypercholesterolemia in a 9-year-old girl.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Not labelled yetRecent Trends in Genetic Testing for Familial Hypercholesterolaemia in Australia.Heart, lung & circulation
Not labelled yetExpectations for Angiopoietin-like 3 Inhibitors Taking Broad Lipid-modifying Effects on the Comprehensive Control of Atherosclerotic Cardiovascular Disease Risk in Patients with Homozygous Familial Hypercholesterolemia.Journal of atherosclerosis and thrombosis
Case reportAutosomal Recessive Hypercholesterolemia Due to a Novel Homozygous LDLRAP1 Frameshift Mutation.JACC. Case reports
Not labelled yetTrends in the Prevalence of Hypercholesterolemia, 2015-2024 - KNHANES.Public health weekly report
Case reportComplex cardiac and porcelain aorta surgery in patients with untreated familial hypercholesterolaemia: a case report.Cardiovascular journal of Africa
Not labelled yetMitochondria-targeted esculetin mitigates age-associated cardiac remodeling through coordinated activation of AMPK-SIRT1 and inhibition of p38 MAPK signaling.Biochemical and biophysical research communications
Not labelled yetPhysical activity and cardiovascular risk factors in familial hypercholesterolemia: A scoping review.Vascular diseases (Paris, France)
Case reportEarly Coronary Atherosclerosis in Homozygous Familial Hypercholesterolemia: The Importance of Aggressive Lipid Lowering.JACC. Case reports
Not labelled yetPaediatric familial hypercholesterolaemia in Australia: a real-world registry study.Archives of disease in childhood
Not labelled yetDurable lipid-lowering beyond 10 years with lomitapide in homozygous familial hypercholesterolemia: A real-world experience in Taiwan.Journal of clinical lipidology
Not labelled yetAge-Specific Behavioral and Clinical Risk Factors for Diabetes, Hypertension, and Hypercholesterolemia.Journal of nutrition education and behavior
Not labelled yetLipid-lowering drugs in heterozygous familial hypercholesterolaemia: a 15-year clinical history.Acta cardiologica
ReviewEvaluating enlicitide decanoate: first oral PCSK9 inhibitor for the treatment of adults with hypercholesterolemia.Expert opinion on pharmacotherapy
Not labelled yetGut microbiome taxonomic and predicted functional profiles in Tunisian individuals with hypercholesterolemia: a pilot study.World journal of microbiology & biotechnology
Review[Treatment of Hypercholesterolemia in Chronic Kidney Disease: Rationale and Therapeutic Approaches from the Non-Dialysis Stage to Kidney Transplantation].Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia
Not labelled yetAge at Menarche, Cardiometabolic Disease Prevalence, and Disease Control in Korean Women: Analysis of the Korea National Health and Nutrition Examination Survey.International journal of medical sciences
Not labelled yetLDL hypercholesterolemia in children: genetic influence and response to lifestyle advice - follow-up of the Fr1dolin-trial.Lipids in health and disease
ReviewMicroRNA modulation and crosstalk of SREBP and NF-κB pathways in herbal nanoparticle therapies for hypercholesterolemia.Fitoterapia
Not labelled yetWhen Cholesterol Can Kill at 20: Recognizing and Managing Homozygous Familial Hypercholesterolemia in the Young.JACC. Case reports
Not labelled yetExcessive hypercholesterolemia in pregnancy alters maternal cardiac remodeling during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology
Not labelled yetUnderstanding Barriers and Motivators of Familial Hypercholesterolemia Genetic Testing: Insights From the Singapore Public.Journal of genetic counseling
Review[Pharmacological properties and clinical efficacy of bempedoic acid (NEXLETOL® tablets 180 mg) for the treatment of hypercholesterolemia].Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Not labelled yetThe mediating effect of attitudes toward genetic testing on the relationship between genetic knowledge of familial hypercholesterolemia and the intention to undergo genetic testing among patients with hyperlipidemia in Korea: a cross-sectional study.Journal of Korean biological nursing science
Not labelled yetLDLR Variant Classification Through Activity-Normalized Prime Editing Screening.Circulation
Not labelled yetThe COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion.Atherosclerosis
Not labelled yetIncreased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia.Lipids in health and disease
Not labelled yetLipid-Laden M1-like Macrophages of Familial Hypercholesterolemia Patients Are Characterized by Increased Interleukin-1β Secretion and Reduced TMEM176A and TMEM176B Gene Expression.Current issues in molecular biology
Not labelled yetResidual Inflammatory Potential in Patients with Treated Non-Definite and Definite Familial Hypercholesterolaemia: A Clinical Study.Journal of personalized medicine
Not labelled yetGenetic Diagnosis and Family Cascade Screening for Familial Hypercholesterolaemia in Patients with Premature Coronary Artery Disease: A Prospective Cohort Study from Vietnam.Journal of personalized medicine
Not labelled yetGenetic Spectrum of Familial Hypercholesterolemia in Russian North-West Registry: Focus on Correlation Between Clinical and Genetic Diagnosis.Journal of cardiovascular development and disease
ReviewSitosterolemia: evolving strategies for earlier diagnosis.Current opinion in lipidology
Not labelled yetEnlicitide (Lipfendra) - an oral PCSK9 inhibitor for LDL-cholesterol lowering.The Medical letter on drugs and therapeutics
Not labelled yetImplementing Genetic Cascade Testing for Familial Hypercholesterolemia in Primary Care: Patient and General Practitioner Experiences.International journal of behavioral medicine
Observational studyClinical Benefits Associated With Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia.Journal of the American Heart Association
Not labelled yetSitosterolemia as a treatable and underrecognized cause of chronic thrombocytopenia beyond ITP: A targeted screening study.Journal of clinical lipidology
Case reportSitosterolemia: A Rare Cause of Severe Hypercholesterolemia in Children.WMJ : official publication of the State Medical Society of Wisconsin
ReviewPlozasiran: a small interfering RNA therapy for hypertriglyceridemia and familial chylomicronemia syndrome.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Observational studyLong-term treatment of homozygous familial hypercholesterolemia with lomitapide: 11 years of safety and effectiveness findings from the Lomitapide Observational Worldwide Evaluation Registry.Journal of clinical lipidology
Not labelled yetEvolocumab for severe refractory hypercholesterolemia in a child with steroid-resistant nephrotic syndrome and membranous nephropathy.Pediatric nephrology (Berlin, Germany)
ReviewEnlicitide: The first oral PCSK9 inhibitor approved for treatment of hypercholesterolemia.Drug discoveries & therapeutics
Not labelled yetCarpe Diem: Genetic Testing for Familial Hypercholesterolemia From Acute Coronary Care to the Community.JACC. Advances
Not labelled yetSevere ischemic cardiomyopathy in a young patient: double genetic burden of familial hypercholesterolemia and elevated lipoprotein(a).Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
Not labelled yetTUDOR, an ascertainment-aware model for LDLR genetic-testing triage in specialist lipid clinics: Development, validation, and UK Biobank transport.Journal of clinical lipidology
Not labelled yetAtorvastatin Mitigates Hypercholesterolemia-Induced Alterations in Cerebral Mitochondrial Dehydrogenases in Rats.International journal of molecular sciences
ReviewDecoding Primary Hyperlipoproteinemias: A Focus on the Pathogenesis and Diagnosis of Familial Hypercholesterolemia and Familial Combined Hyperlipidemia.Diagnostics (Basel, Switzerland)
Not labelled yetBirth and first-year outcomes in infants of mothers with familial hypercholesterolemia or atherosclerotic cardiovascular disease in the US: A retrospective cohort study.Journal of clinical lipidology
Not labelled yetBeyond sitosterol: A multivariable sterol model improves diagnosis of pediatric sitosterolemia in the gray zone.Journal of clinical lipidology
Not labelled yetPredicting genetically defined familial hypercholesterolemia with the FAMCAT algorithm in an Australian tertiary clinic.Journal of clinical lipidology
Meta-analysisEfficacy and Safety of Oral PCSK9 Inhibitors in Adults With Hypercholesterolemia: An Updated and GRADE Assessed Systematic Review and Meta-Analysis of Randomised Controlled Trials.Diabetes, obesity & metabolism
In plain wordsRead moreRead the paper on PubMed