Ankylosing spondylitis: trials for referral
120 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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120 trials shown
Phase 165 sites
RecruitingBulgaria, Czechia, Germany, Poland, Slovakia, United States
NCT07290036
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
UCB Biopharma SRL
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07915544
A Study of GKL-006Allo Injection in Patients With Ankylosing Spondylitis
Beijing Gene Key Life Technology Co., Ltd
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 40 sites
Not yet recruiting
NCT07894497
Ivarmacitinib With or Without Celecoxib for Ankylosing Spondylitis
Peking University Third Hospital
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 2107 sites
RecruitingBrazil, Canada, Chile, China, Colombia, Germany
NCT07133633
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Merck Sharp & Dohme LLC
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govPhase 323 sites
RecruitingCanada, Germany, Spain, France, United Kingdom, Poland
NCT06668181
An Open-label Study to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-related Arthritis (Including Juvenile-onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis
UCB Biopharma SRL
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govPhase 41 site
Not yet recruitingUnited States
NCT07770646
A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial Spondyloarthritis
The University of Texas Health Science Center, Houston
Registry updated 14 Oct 2026
Registry record: ClinicalTrials.govPhase 328 sites
Not yet recruitingFrance
NCT07836283
Evaluation of the Efficacy and Safety of Bimekizumab (BZK) or Adalimumab (ADA) in the Treatment of Anterior Chest Wall Pain Associated With Active Axial Spondyloarthritis Refractory to NSAIDs With Hypothesis of Superiority of Bimekizumab
University Hospital, Rouen
Registry updated 23 Sept 2026
Registry record: ClinicalTrials.govPhase 1/216 sites
RecruitingAustralia, Belgium, Germany, Spain, Netherlands, Poland
NCT07047703
EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)
Grey Wolf Therapeutics
Registry updated 18 Sept 2026
Registry record: ClinicalTrials.govPhase 114 sites
RecruitingCanada, Switzerland, Germany, Spain, United States
NCT06888193
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
Registry updated 18 Sept 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingNorway
NCT06451588
Fecal Microbiota Transplantation in Axial Spondyloarthritis
University Hospital of North Norway
Registry updated 14 Aug 2026
Registry record: ClinicalTrials.govPhase 42 sites
RecruitingBrazil
NCT07087912
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
University of Sao Paulo General Hospital
Registry updated 20 Jul 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07138898
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
NYU Langone Health
Registry updated 9 Jul 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07632599
Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing Spondylitis
Eighth Affiliated Hospital, Sun Yat-sen University
Registry updated 8 Jun 2026
Registry record: ClinicalTrials.govPhase 417 sites
RecruitingSpain
NCT07611747
Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)
Instituto de Investigación Marqués de Valdecilla
Registry updated 28 May 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT06526377
Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for Efficacy
XBiotech, Inc.
Registry updated 14 May 2026
Registry record: ClinicalTrials.govPhase 41 site
Not yet recruitingChina
NCT07582146
Effectiveness and Safety of Acemetacin in Active Axial Spondyloarthritis: A Real-world Study
Chinese PLA General Hospital
Registry updated 12 May 2026
Registry record: ClinicalTrials.govNo phase7 sites
RecruitingGermany
NCT07561255
Exploratory Investigation of the Acceptance and Utility of 14-day Trial Periods and Application-related Outcome Measurement (AbEM) Within the Routine Prescription of the DiGA Axia.
Wuerzburg University Hospital
Registry updated 1 May 2026
Registry record: ClinicalTrials.govPhase 1/20 sites
Not yet recruiting
NCT07534644
A Phase I/Ⅱ Clinical Trial for Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Ankylosing Spondylitis
Shenzhen Huishan Biotechnology Co., Ltd.
Registry updated 20 Apr 2026
Registry record: ClinicalTrials.govPhase 419 sites
RecruitingBelgium, Canada, Poland, United States
NCT06454188
A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis
CARE ARTHRITIS LTD.
Registry updated 3 Apr 2026
Registry record: ClinicalTrials.govPhase 414 sites
Not yet recruitingBulgaria, Germany, Spain, France, Netherlands, Poland
NCT07018206
Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis
CARE ARTHRITIS LTD.
Registry updated 6 Feb 2026
Registry record: ClinicalTrials.govPhase 42 sites
RecruitingChina
NCT05303285
A Study Evaluating the Efficacy of Secukinumab 300mg in Chinese Adults With Active Ankylosing Spondylitis
Tongji Hospital
Registry updated 27 Jan 2026
Registry record: ClinicalTrials.govPhase 31 site
Not yet recruitingChina
NCT07349329
A Study to Evaluate the Efficacy and Safty of 608 in Patients With Non- Radiographic Axial Spondyloarthritis (Nr-axSpA)
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Registry updated 16 Jan 2026
Registry record: ClinicalTrials.govPhase 2/31 site
Not yet recruitingChina
NCT07339566
Efficacy and Safety of Xeligekimab in the Treatment of Non-Radiographic Axial Spondyloarthritis
Lingli Dong
Registry updated 14 Jan 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT07172360
Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.
Jiangsu vcare pharmaceutical technology co., LTD
Registry updated 2 Jan 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT07261644
A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS)
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Registry updated 10 Dec 2025
Registry record: ClinicalTrials.govPhase 21 site
RecruitingDenmark
NCT04924270
Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases
Odense University Hospital
Pre-treatment window Registry sentence: “Newly diagnosis of treatment-naïve RA, AS, PsA, PSar, CD, or UC.”
Registry updated 5 Dec 2025
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT07237568
A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing Spondylitis
Lynk Pharmaceuticals Co., Ltd
Registry updated 20 Nov 2025
Registry record: ClinicalTrials.govPhase 411 sites
RecruitingNetherlands
NCT07160231
REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases
Sint Maartenskliniek
Registry updated 17 Sept 2025
Registry record: ClinicalTrials.govPhase 45 sites
RecruitingChina
NCT06707194
Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis
Nanfang Hospital, Southern Medical University
Registry updated 26 Jun 2025
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT06860750
A Trial of SHR-1314 Injection in Adult Patients With Active Non-radiographic Axial Spondyloarthritis
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Registry updated 22 Jun 2025
Registry record: ClinicalTrials.gov
The same sites as a list
- China24 open trials
- United States16 open trials
- Germany15 open trials
- France15 open trials
- Türkiye14 open trials
- Poland9 open trials
- Spain7 open trials
- South Korea6 open trials
- Netherlands5 open trials
- United Kingdom5 open trials
- Canada5 open trials
- Belgium5 open trials
- Denmark4 open trials
- Egypt4 open trials
- Bulgaria3 open trials
- Sweden3 open trials
- Czechia2 open trials
- Brazil2 open trials
- Norway2 open trials
- Italy2 open trials
- Portugal2 open trials
- Slovakia1 open trial
- Ukraine1 open trial
- Colombia1 open trial
- Taiwan1 open trial
- Chile1 open trial
- Australia1 open trial
- Switzerland1 open trial
- Pakistan1 open trial
- Greece1 open trial
- Singapore1 open trial
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
What changed in the last 7 days
Registry facts, one per line, newest first.
Status changed: Running, not recruiting → Completed
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
NCT02281747 · No phase · United States
Source: ClinicalTrials.govOpened for recruitment
Identification of Serum Level of Glutathione Peroxidase 4
NCT06554392 · No phase · Egypt
Source: ClinicalTrials.govClosed for recruitment
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
NCT05785611 · Phase 3 · Belgium, Bulgaria, Czechia, Germany, Estonia, Spain
Source: ClinicalTrials.govOpened for recruitment
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
NCT05785611 · Phase 3 · Belgium, Bulgaria, Czechia, Germany, Estonia, Spain
Source: ClinicalTrials.govNew in the registry
A Study of GKL-006Allo Injection in Patients With Ankylosing Spondylitis
NCT07915544 · Phase 1 · China
Source: ClinicalTrials.gov
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 4 Nov 2026
Completed521292 participants
NCT02281747
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
No phaseEnded 10 Sept 2026
Completed238 participants
NCT06587828
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
Phase 3Ended 9 Aug 2026
Completed508 participants
NCT04436640
A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis
- Bimekizumab longer-term safety profile in adult patients with axial spondyloarthritis or psoriatic arthritis: an updated analysis of six phase IIb/III clinical studies. · RMD open, 2026
- Sustained improvements in spinal pain, morning stiffness, fatigue, sleep, physical function and overall health-related quality of life with bimekizumab in patients with axial spondyloarthritis: 2-year results from two phase 3 studies. · RMD open, 2025
- Bimekizumab treatment for sustained improvements in patient symptoms and health-related quality of life to 3 years in axial spondyloarthritis: results from the BE MOBILE studies and their open-label extension. · RMD open, 2026
No phaseEnded 31 Jul 2026
No phaseEnded 30 Jul 2026
Phase 2Ended 17 Jun 2026
Completed265 participants
NCT06250062
A Clinical Study of JS005 in Patients With Ankylosing Spondylitis
No phaseEnded 1 May 2026
Completed50 participants
NCT07891507
Nurse-Led Exercise Program for Older Adults With Ankylosing Spondylitis
No phaseEnded 18 Mar 2026
No phaseEnded 5 Mar 2026
Completed6967 participants
NCT07580092
Construct Validity and Responsiveness of EQ-5D-3L and EQ-5D-5L in Patients With Inflammatory Joint Disease
Phase 3Ended 4 Mar 2026
Completed207 participants
NCT05861128
Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS)
No phaseEnded 23 Feb 2026
No phaseEnded 15 Feb 2026
Paused300 participants
NCT05450133
Hematological Parameters in Axial Spondyloarthritis
Reason given: primary researcher is not avaible to recruit participants
No phaseEnded 29 Jan 2026
No phaseEnded 5 Jan 2026
Completed16 participants
NCT06555562
Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis
Phase 2Ended 5 Jan 2026
Completed25 participants
2024-513498-36-00
A Phase 2 open-label imaging study to explore the effects of sonelokimab in patients with active axial spondyloarthritis
No phaseEnded 31 Dec 2025
No phaseEnded 31 Dec 2025
No phaseEnded 31 Dec 2025
Completed30 participants
NCT07821541
Changes in Serum Calprotectin and Their Clinical Correlates in Axial Spondyloarthritis Patients Undergoing Pulmonary Rehabilitation
Phase 4Ended 22 Dec 2025
Completed10 participants
2023-508976-12-00
Rapid pain control in Ixekizumab targeted axial spondyloarthritis
No phaseEnded 18 Dec 2025
Completed70 participants
NCT01969188
A Study of Novel Immune Modulating Biomarkers in Patients With Spondyloarthritis With Axial Involvement
Show more
No phaseEnded 5 Dec 2025
Completed27 participants
NCT06535776
Effects of Matrix Rhythm Therapy in Axial Spondyloarthritis Patients
No phaseEnded 30 Nov 2025
Phase 3Ended 14 Nov 2025
Completed323 participants
NCT07498634
Recombinant Anti-human IL-17A/F Humanized Monoclonal Antibody Injection in the Treatment of Moderate-to-Severe Active AS
Phase 3Ended 7 Nov 2025
Completed510 participants
NCT06378697
A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis
No phaseEnded 30 Oct 2025
No phaseEnded 28 Oct 2025
Completed52 participants
NCT07515131
Respiratory Function and S-index in Radiographic Axial Spondyloarthritis
No phaseEnded 5 Sept 2025
No phaseEnded 25 Aug 2025
No phaseEnded 20 Aug 2025
Completed127 participants
NCT05155098
2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
No phaseEnded 19 Aug 2025
Completed50 participants
NCT05006690
Telerehabilitation and Face-to-Face Clinical Pilates-Based Exercise in Individuals With Axial Spondyloarthritis
No phaseEnded 1 Aug 2025
Completed200 participants
NCT07130331
Efficacy and Influencing Factors of Secukinumab in Patients With Axial Spondyloarthritis
Phase 4Ended 4 Jul 2025
Completed104 participants
2023-505050-18-00
Tofacitinib in early active axial spondyloarthritis: a prospective, randomized, double-blind, placebo-controlled multicentre study - FASTLANE
Phase 3Ended 9 Jun 2025
Completed265 participants
NCT05861102
Efficacy and Safety Study of Jaktinib in Subjects With Active Ankylosing Spondylitis(AS)
No phaseEnded 31 May 2025
Completed201 participants
NCT07054749
Artificial Intelligence Literacy and E-Health Literacy in Rheumatic Diseases
- Digital and artificial intelligence literacy in inflammatory rheumatic and degenerative joint diseases. · Advances in medical sciences, 2026
No phaseEnded 22 May 2025
Completed80 participants
NCT06652984
Effectiveness of Mobile Respiratory Training in Ankylosing Spondylitis
Phase 3Ended 16 May 2025
No phaseEnded 10 Apr 2025
Completed70 participants
NCT06727266
Ultrasonographic Evaluation of the Shoulder Joint in Patients With Axial Spondyloarthritis
No phaseEnded 3 Apr 2025
Phase 3Ended 28 Feb 2025
Completed734 participants
NCT04169373
A Study to Evaluate Efficacy and Safety of Upadacitinib in Adults With Axial Spondyloarthritis
Phase 3Ended 14 Feb 2025
Completed137 participants
NCT04732117
Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis
No phaseEnded 12 Jan 2025
Completed56 participants
NCT05968469
The Effects of Aerobic Exercise in Patients With Ankylosing Spondylitis
No phaseEnded 31 Dec 2024
Completed162 participants
NCT06873074
A Retrospective Cohort Study About Surgical Efficacy for Lower Cervical Fractures in Ankylosing Spondylitis
No phaseEnded 30 Dec 2024
No phaseEnded 13 Dec 2024
Completed377 participants
NCT05779969
Comparison of CT Scan Between Patients With Axial Spondyloarthritis and Control Subjects
No phaseEnded 10 Dec 2024
Completed72 participants
NCT05433168
Study Evaluating the Effectiveness of Shiatsu on Fatigue in Patients With Axial Spondyloarthritis
Early Phase 1Ended 15 Oct 2024
Withdrawn before start0 participants
NCT05119712
Terbinafine Treatment of Axial Spondyloarthropathy
Reason given: Study stopped due to poor recruitment.
Phase 4Ended 1 Oct 2024
Completed300 participants
NCT03445845
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis
Phase 3Ended Sept 2024
Withdrawn before start0 participants
NCT04483687
Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy
Reason given: Development program terminated
No phaseEnded 30 Sept 2024
Completed77651 participants
NCT06568029
Construct Validity and Responsiveness of EQ-5D-3L in Patients With Rheumatic Disease
No phaseEnded 1 Aug 2024
Phase 3Ended 4 Jul 2024
No phaseEnded 30 Jun 2024
Completed50 participants
NCT06000072
Comparison of Tele-rehabilitation or Video-Based Core Exercises in Individuals With Axial Spondyloarthritis
Phase 3Ended Jun 2024
Withdrawn before start0 participants
NCT04483700
Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy
Reason given: Development program terminated
No phaseEnded 28 Jun 2024
Completed318 participants
NCT05961267
Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism
- Cervical cancer screening practices among patients with autoimmune and inflammatory rheumatic diseases: a descriptive cross-sectional observational study. · BMC women's health, 2026
- Prevalence of effective contraceptive use among patients with rheumatic diseases: a descriptive study. · BMC rheumatology, 2026
No phaseEnded 23 Jun 2024
No phaseEnded 27 May 2024
Completed102 participants
NCT06230952
Reliability of BASDAI and BASFI Applied by Tele-Assessment Method in Axial SpA Spondyloarthritis
Phase 3Ended 21 May 2024
Completed465 participants
NCT05881785
Study of Efficacy and Safety of GR1501 in Patients with Radiographic Axial Spondyloarthritis
- Xeligekimab, an Interleukin-17A Antagonist for Active Radiographic Axial Spondyloarthritis in Chinese Patients: 16- and 48-Week Results from a Phase III, Randomized, Double-Blind, Placebo-Controlled Study. · BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2026
Phase 2Ended 11 May 2024
Completed180 participants
NCT05814939
Efficacy and Safety Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.
No phaseEnded 5 May 2024
No phaseEnded Apr 2024
Not medical advice. fetched 8 Nov 2026