Hepatitis B: trials for referral
239 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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239 trials shown
No phase1 site
RecruitingUnited States
NCT00001971
Evaluation of Patients With Liver Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 40 sites
Not yet recruiting
NCT07908459
B-Ensure: Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants
GlaxoSmithKline
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07903831
Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B
Sinocelltech Ltd.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07031219
HIV/HBV/HCV Triple Screening in Primary Care
University of Texas Southwestern Medical Center
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 210 sites
RecruitingCanada, Spain, France, United Kingdom, Italy, United States
NCT07654283
Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions
AusperBio Therapeutics Inc.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 10 sites
Not yet recruiting
NCT07905157
A Study to Compare Blood Levels of Bepirovirsen and Safety Using Different Methods of Injecting in Healthy Adult Participants
GlaxoSmithKline
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT07267208
A Prospective Study to Evaluate the Efficacy and Safety of Entecavir ODT Conversion in Stable Liver Transplant Patients
Jongman Kim
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 1/20 sites
Not yet recruiting
NCT07897448
A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)
Grand Theravac Life Sciences (Hangzhou) Co., Ltd.
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 214 sites
RecruitingChina
NCT06650852
A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)
Brii Biosciences Limited
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT04690972
"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
Institut National de la Santé Et de la Recherche Médicale, France
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07884864
A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants
Ausper Biopharma Co., Ltd.
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingTaiwan
NCT04970836
The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort
National Taiwan University Hospital
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govPhase 1/20 sites
Not yet recruiting
NCT07876856
A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)
Ausper Biopharma Co., Ltd.
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govPhase 41 site
By invitation onlyChina
NCT07542951
TAF vs TDF During the Pregancy
The Third Affiliated Hospital of Guangzhou Medical University
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyZambia
NCT07875218
Integrating Hepatitis B Elimination Into the HIV Program in Zambia
Centre for Infectious Disease Research in Zambia
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govPhase 40 sites
Not yet recruiting
NCT07560046
Combating Related Epidemics in HCV
Duke University
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govNo phase10 sites
Recruiting
NCT07459426
Entecavir Resistance-Associated Mutations in Chronic HBV Patients in Turkey (STREAM Study)
Yaşar Bayındır, MD
Pre-treatment window Registry sentence: “Group 1: Either treatment-naïve participants with HBV DNA\>2000 IU/ml”
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.govPhase 210 sites
RecruitingAustralia, China, Japan, South Korea, New Zealand, Singapore
NCT07370207
Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
AusperBio Therapeutics Inc.
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingVietnam
NCT07054359
"HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent Mother-to-child Transmission"
ANRS, Emerging Infectious Diseases
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT03025074
Blood Collection Biorepository for Liver Disease Research
State University of New York at Buffalo
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.govPhase 1/21 site
Not yet recruitingBangladesh
NCT07855172
Safety and Immunogenicity of a Combined Diphtheria, Tetanus, Whole Cell Pertussis, Hepatitis B, Recombinant Poliomyelitis and Haemophilus Influenzae Type b (Hib) Vaccine (SIIPL DTwP-HepB-rPV-Hib)
Serum Institute of India Pvt. Ltd.
Registry updated 6 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingGermany
NCT05051098
A Non-interventional Registry for Patients With Hepatitis B Virus Infection
Hannover Medical School
Registry updated 5 Oct 2026
Registry record: ClinicalTrials.govPhase 30 sites
Not yet recruiting
NCT07854847
Study Interchangeability Hep-B Vaccine Administered at Birth Dose
PT Bio Farma
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT07855029
Impact of Functional Cure of Chronic Hepatitis B on Patient-Reported Outcomes (PROs)
Zhiliang Gao
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
RecruitingSouth Africa
NCT07563309
A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid Test
bioLytical Laboratories
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
RecruitingVietnam
NCT06638320
Hepatitis Delta Virus Infection: Cross-sectional Study in Patients With Chronic Hepatitis B Virus Infection
Tam Anh Research Institute
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govPhase 377 sites
Not yet recruitingChina
NCT07797231
Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor Response
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingChina
NCT07852091
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (A)
The Second Affiliated Hospital of Chongqing Medical University
Registry updated 1 Oct 2026
Registry record: ClinicalTrials.govPhase 213 sites
RecruitingUnited States
NCT05832229
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingChina
NCT07845058
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (B)
The Second Affiliated Hospital of Chongqing Medical University
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- China102 open trials
- France20 open trials
- United States19 open trials
- Hong Kong SAR China11 open trials
- Taiwan8 open trials
- New Zealand8 open trials
- Australia7 open trials
- Italy6 open trials
- Germany6 open trials
- United Kingdom5 open trials
- South Korea5 open trials
- Moldova5 open trials
- Romania5 open trials
- Spain4 open trials
- Singapore4 open trials
- Denmark4 open trials
- Canada3 open trials
- Vietnam3 open trials
- Egypt3 open trials
- Zambia2 open trials
- Japan2 open trials
- Bangladesh2 open trials
- Ukraine2 open trials
- Switzerland2 open trials
- Argentina2 open trials
- Austria2 open trials
- Bulgaria2 open trials
- Thailand2 open trials
- Indonesia2 open trials
- South Africa1 open trials
- Brazil1 open trials
- Peru1 open trials
- Kenya1 open trials
- Côte d’Ivoire1 open trials
- Netherlands1 open trials
- Czechia1 open trials
- Portugal1 open trials
- Israel1 open trials
- Poland1 open trials
- Greece1 open trials
- Russia1 open trials
- Luxembourg1 open trials
- Estonia1 open trials
- Serbia1 open trials
- Finland1 open trials
- Belarus1 open trials
- Hungary1 open trials
- Ireland1 open trials
- Belgium1 open trials
- Sweden1 open trials
- Georgia1 open trials
- Croatia1 open trials
- Latvia1 open trials
- India1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
Madrid, Spain
0 trials · 30 publications · ROR
Centro de Investigación Biomédica en Red Enfermedades Infecciosas
Madrid, Spain
0 trials · 19 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 40 publications · ROR
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
Barcelona, Spain
0 trials · 26 publications · ROR
First Affiliated Hospital of Wenzhou Medical University
Wenzhou, China
0 trials · 24 publications · ROR
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
9 trials · 49 publications · ROR
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung, Taiwan
10 trials · 52 publications · ROR
National Clinical Research Center for Digestive Diseases
Beijing, China
0 trials · 20 publications · ROR
Second Affiliated Hospital of Chongqing Medical University
Chongqing, China
0 trials · 44 publications · ROR
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
Hangzhou, China
0 trials · 38 publications · ROR
The Affiliated Yongchuan Hospital of Chongqing Medical University
Chongqing, China
0 trials · 20 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
0 trials · 19 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
0 trials · 19 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
No registry change in the last 7 days.
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 30 Sept 2026
Completed210 participants
NCT05490836
Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB Patients
No phaseEnded 1 Sept 2026
Completed1201 participants
NCT07843446
Residual Histological Disease Across Treatment Pathways in Chronic Hepatitis B
Phase 1Ended 19 Aug 2026
No phaseEnded 10 Aug 2026
Completed104 participants
NCT07784452
Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis
Phase 1Ended 10 Aug 2026
Completed16 participants
NCT06989788
A Study to Evaluate the Safety and Immunogenicity of an Investigational Vaccine for Chronic Hepatitis B Virus Infection, in Healthy Adults
Phase 2Ended 5 Aug 2026
Phase 1Ended 29 Jul 2026
Phase 3Ended 28 Jul 2026
Completed337 participants
NCT07343778
A Clinical Trial Evaluating the Safety of Hydronidone Capsules in Patients With Hepatic Fibrosis and Liver Cirrhosis
Phase 2Ended 27 Jul 2026
Completed67 participants
NCT07417553
A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis
Phase 4Ended 30 Jun 2026
Completed140 participants
NCT04782375
Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B
Phase 2Ended 29 Jun 2026
Completed30 participants
NCT04294498
Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection
Phase 2Ended 22 Jun 2026
Completed411 participants
NCT07364448
A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis
Phase 1Ended 1 Jun 2026
Completed4 participants
NCT06062966
The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)
No phaseEnded 31 May 2026
Completed1000 participants
NCT07730736
Analysis of Clinical Characteristics of Chronic Hepatitis B Combined With MAFLD in Different TCM Syndrome Types
No phaseEnded 31 May 2026
Completed85 participants
NCT07865520
Alcohol Consumption and Plasma cfDNA Methylation in Chronic Hepatitis B
Phase 1Ended 29 May 2026
Phase 1Ended 21 May 2026
Completed26 participants
NCT05727267
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Phase 1Ended 11 May 2026
Completed30 participants
NCT07394309
Study of Hydroxynidone Capsules in Patients With Hepatic Impairment and Matched Healthy Controls
Phase 1Ended 6 May 2026
Phase 4Ended 20 Apr 2026
Completed134 participants
NCT07084948
Inhibition of HBV Replication and Biological Reversal of Cirrhosis (F3-F4) and HCC by Flavonoids
Phase 3Ended 15 Apr 2026
Completed981 participants
NCT05630807
Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)
Phase 3Ended 13 Apr 2026
Completed857 participants
NCT05630820
Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 2)
Phase 2Ended 8 Apr 2026
Completed29 participants
NCT05551273
Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV
Phase 1Ended 8 Apr 2026
Phase 1Ended 31 Mar 2026
Completed35 participants
NCT06070051
Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy
No phaseEnded 30 Mar 2026
Phase 2Ended 16 Mar 2026
Completed244 participants
NCT04856085
Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection
No phaseEnded 5 Mar 2026
Completed21210 participants
NCT04904835
Access HBV Assays - European Union (EU) Clinical Trial Protocol -
No phaseEnded 1 Mar 2026
Completed100 participants
NCT05967650
Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients
No phaseEnded 26 Feb 2026
Completed274 participants
NCT05621304
Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)
Phase 3Ended 20 Feb 2026
Completed1557 participants
NCT06413121
Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV
Phase 1Ended 9 Feb 2026
Completed128 participants
NCT05960240
Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.
Phase 2Ended 26 Jan 2026
Completed86 participants
NCT06550128
Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB).
Phase 2Ended 23 Jan 2026
Completed86 participants
NCT05970289
Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients
No phaseEnded 15 Jan 2026
Completed713 participants
NCT06793826
Post-marketing Surveillance Study for the Safety of a DTaP-IPV- HB-PRP~T Vaccine in Republic of Korea
Phase 2Ended 13 Jan 2026
No phaseEnded 31 Dec 2025
Completed300 participants
NCT07730905
Analysis of Renal Impairment Characteristics and High-Risk Factors in Chronic Hepatitis B Patients on Long-Term Oral Nucleos(t)Ide Analogues
Phase 1Ended 29 Dec 2025
Completed32 participants
NCT07595159
A Study of BW-20507 in Chinese Healthy Subjects and Subjects With Chronic Hepatitis B
Phase 1/2Ended 16 Dec 2025
Completed24 participants
NCT05330455
Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection
Phase 1Ended 15 Dec 2025
Completed36 participants
NCT07515209
A Clinical Study of HH-006 in Untreated Chronic Hepatitis B Virus Infected Patients
Phase 2Ended 10 Dec 2025
No phaseEnded 30 Nov 2025
Completed401 participants
NCT06901362
Seroprevalence and Vaccination Rate of Hepatitis B Virus and Varicella-zoster Virus Among Medical Students Under Immunizing Program
Phase 4Ended 25 Nov 2025
Phase 1/2Ended 10 Nov 2025
Completed129 participants
NCT06115993
A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) Patients
Phase 2Ended 15 Oct 2025
Completed24 participants
2023-503880-40-00
A trial to evaluate safety and characteristics of a substance for treatment of chronic hepatitis
Phase 2Ended 15 Oct 2025
Phase 2Ended 21 Aug 2025
Completed32 participants
2024-514888-25-00
HepBTer: From fungus to virus, a phase 2a clinical trial investigating the safety and efficacy of terbinafine in chronic hepatitis B patients
Phase 1/2Ended 19 Aug 2025
Completed33 participants
NCT05612581
A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection
Phase 2Ended 5 Aug 2025
Completed174 participants
NCT05276297
A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy
Phase 2Ended 31 Jul 2025
Completed20 participants
NCT05345990
Effective treatment of Hepatitis B with specific immune antibodies
Phase 1Ended 16 Jun 2025
No phaseEnded 13 Jun 2025
Completed250 participants
NCT07637214
A Real-world Study: Analysis of the Efficacy of Antiviral Therapy in CHB Patients Over 30 Years Old, HBV DNA Positive and ALT Normal
Phase 2Ended 21 May 2025
Completed43 participants
NCT04980482
Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection
Phase 1Ended 14 May 2025
Completed20 participants
NCT06384131
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection
Phase 1Ended 28 Apr 2025
Completed46 participants
NCT06422767
Study to Evaluate the Effect of Bepirovirsen on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers
No phaseEnded 22 Apr 2025
Completed80 participants
NCT07185152
The Effect of Mechanical Vibration and Flick Tapping Methods in Reducing Pain in Infant Vaccination
No phaseEnded 11 Apr 2025
Completed84 participants
NCT06221605
Composite Probiotics Stabilize Lipid Metabolism in Chronic Hepatitis B Patients:A Clinical Trial
No phaseEnded 4 Apr 2025
Completed233 participants
NCT05669677
Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease
Phase 2Ended 5 Mar 2025
Completed52 participants
NCT04535544
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus
Phase 1Ended 18 Feb 2025
Completed30 participants
NCT05828745
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis B
Not medical advice. fetched 4 Nov 2026