Obesity: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• GLP-1 170
• PPAR 0
• FTO 0
• AMPK 3
• GIP 20
• SGLT2 5
• STAT3 0
• SIRT1 0
• PI3K 0
• NRF2 0
• AKT 0
• mTOR 2
• NLRP3 3
• MAPK 0
• TP53 0
• TNF 0
• IL-6 1
• TLR4 0
• BDNF 2
• DPP-4 1
• JNK 0
• APOE 0
• ERK 0
• IL-17 1
• PTEN 0
• STING 0
• ACE2 0
• HIF-1 0
• PCSK9 0
• VEGF 0
• IL-1 0
• JAK 0
• PNPLA3 2
• YAP 0
• HMGB1 0
• CTNNB1 0
• HER2 0
• MMP-9 0
• PD-L1 0
• PINK1 0
• TFEB 0
• TREM2 0
• CCR5 0
• FGFR 0
• GPX4 0
• IGF1R 0
• IL-23 0
• METTL3 0
• PD-1 0
• STK11 0
• AR 0
• BCL-2 0
• CFTR 0
• COX-2 0
• HDAC 0
• EGFR 0
• HSP90 0
• MEK 0
• MYC 0
• PKM2 0

24 of 8,751 institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Elucidating the role of maternal nutrient stores in the metabolism of the preimplantation embryo (MaterMeta)

  Kobenhavns Universitet· Kobenhavn, Denmark· EU contribution €247,553· until Aug 2029

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Studying the role of Tbx-3 expressing neurons during obesity and ageing (OBrAgeing)

  Institut National de la Sante Et de la Recherche Medicale· Paris, France· EU contribution €226,421· until Aug 2029

• European Commission (Horizon Europe) · HORIZON-ERC

  Selective Sensory Vagal Interface: a bionic platform for internal organ modulation (VisceraLink)

  Medizinische Universitaet Wien· Wien, Austria· EU contribution €2,210,625· until Dec 2031

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-DN

  Metabolic disease heterogeneity definition, prevention and remission with targeted interventions (MEDIculous REMeDy)

  Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit und Umwelt Gmbh· Neuherberg, Germany· EU contribution €4,437,236· until Dec 2030· 11 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-DN

  Bridging Chronobiology and Physiology through Expert Training (ChronoBridge)

  Ecole Polytechnique Federale de Lausanne· Lausanne, Switzerland· EU contribution €3,885,022· until Dec 2030· 9 countries

  The disease is named only in the funder's project summary, not in the title.

5 of 127 running projects, newest first. Listed amounts together: €430.1m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Terminated, withdrawn and suspended trials with the reason the sponsor gave in the registry, quoted word for word.

• Terminated

  Physical Exercise Prehabilitation Program in mEtabolic suRgery

  NCT06889207· Flevoziekenhuis· Updated 12 Nov 2026

  “Higher dropout rate (38% versus the 10% on which the original sample size was based). Interim analysis revealed that the effect on the primary outcome measure was already highly statistically significant.”Registry text, quoted unchanged. Source

• Suspended

  Molecular and Clinical Profile of Diabetes Mellitus and Its Complications

  NCT01105858· National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)· Updated 12 Nov 2026

  “Recruitment temporarily paused.”Registry text, quoted unchanged. Source

• Terminated

  Small Bowel Diversion

  NCT06374368· University of Ostrava· Updated 6 Nov 2026

  “Halted for safety concerns after jejuno-colic diversion: frequent and serious late complications, incl. hepatic fibrosis, lean body mass loss and surgical reversal of the anastomosis.”Registry text, quoted unchanged. Source

• Terminated

  Probiotics and Insulin Resistance in Obese Asthmatics

  NCT05949255· University of Alabama at Birmingham· Updated 5 Nov 2026

  “Lost coordinator and statistician before no cost extension study could be completed.”Registry text, quoted unchanged. Source

• Suspended

  The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity

  NCT07423065· University of Primorska· Updated 4 Nov 2026

  “The study has been temporarily suspended pending approval from the Slovenian Agency for Medicinal Products and Medical Devices (JAZMP). The need for this additional regulatory approval was identified following communication with JAZMP.”Registry text, quoted unchanged. Source

• Withdrawn

  GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial Emulation

  NCT07677865· West China Hospital· Updated 16 Oct 2026

  “poor accrual and funding issues”Registry text, quoted unchanged. Source

• Terminated

  A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

  NCT07553299· Verdiva Bio Dev Limited· Updated 13 Oct 2026

  “The Study Sponsor made a business decision not to continue the study. The decision was not based on safety findings.”Registry text, quoted unchanged. Source

• Withdrawn

  An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities

  NCT05532020· Soleno Therapeutics, Inc.· Updated 13 Oct 2026

  “Company Decision”Registry text, quoted unchanged. Source

• Terminated

  Weight Management Program for Obese Preschool Children

  NCT07126210· Peking University· Updated 16 Sept 2026

  “Study terminated prematurely due to poor accrual. The actual number of eligible children recruited from kindergartens was far lower than expected, making the study unfeasible.”Registry text, quoted unchanged. Source

• Suspended

  A Food Security Intervention for the Prevention of Cancer in Low-income Families

  NCT07039630· Roswell Park Cancer Institute· Updated 15 Sept 2026

  “behavioral intervention is being prepared”Registry text, quoted unchanged. Source

Trials whose registry record says individual participant data (IPD) will be shared.

• Use of a Mandibular Advancement Appliance in Children With Obstructive Sleep Apnea

  NCT07902908· National Institute of Dental and Craniofacial Research (NIDCR)· Source

• School- and Family-Based Lifestyle Programme for Primary School Children in Punjab, Pakistan: A Feasibility Study

  NCT07932028· Central South University· Source

• Aerobic Exercise Added to Diaphragmatic Breathing for Nocturnal Enuresis in Overweight and Obese Children

  NCT07930351· Hungarian University of Sports Science· Source

• A Study to Evaluate ALN-2232 in Participants With Obesity

  NCT07463846· Alnylam Pharmaceuticals· Source

• E-Bike Commuting and Health in Overweight College Students

  NCT07114991· University of Wisconsin, River Falls· Source

• A Novel Obesity Prevention Program for High-Risk Infants in Primary Care

  NCT06028113· Children's Hospital Medical Center, Cincinnati· Source

• Family Grocery Study R01

  NCT07806721· State University of New York at Buffalo· Source

• Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)

  2024-516654-22-00· Amgen Inc.· Source

• A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

  NCT05556512· Eli Lilly and Company· Source

• HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking

  NCT06952348· Karolinska Institutet· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 21
• Organoids 10
• Mendelian Randomization Analysis 179
• CRISPR-Cas Systems 7
• Gene Expression Profiling 144
• Sequence Analysis, RNA 10
• Whole Genome Sequencing 4
• Exome Sequencing 19
• Proteomics 127
• Metabolomics 190
• Mass Spectrometry 28
• Flow Cytometry 16
• Immunohistochemistry 41
• Xenograft Model Antitumor Assays 15
• Positron-Emission Tomography 25
• Magnetic Resonance Imaging 258
• Machine Learning 155
• Deep Learning 20
• Cohort Studies 1013
• Genome-Wide Association Study 202

• PET Imaging of Dual GLP-1R and GIPR Targeting with [18F]AlF-NOTA-Asp2-Tirzepatide.

  Mol Pharm, Nov 2026

• Deep progressive learning reconstruction for fast and low-dose whole-body PET scans in an integrated PET/MR system.

  BMC Med Imaging, Jul 2026

• Branched-chain and glucogenic amino acids predict brown fat recruitment and metabolic clearance in adults with overweight or obesity.

  Am J Physiol Endocrinol Metab, Jun 2026

• A Four-Week Treatment With Dapagliflozin Is Associated With a Reduction in Insulin-Stimulated Renal Cortical Glucose Uptake: A Post Hoc Analysis From a Pilot Study.

  Diabetes Obes Metab, Jun 2026

• Abdominal adiposity and Alzheimer's disease imaging markers across sex and race at midlife.

  J Alzheimers Dis, Jun 2026

• Brain Serotonin Transporter Is Elevated in Obesity: Bayesian and Frequentist Meta-Analyses.

  Diabetes Obes Metab, May 2026

• Improved assessment of coronary artery disease in obese patients with flurpiridaz-18F positron emission tomography myocardial perfusion imaging: A prespecified subgroup analysis of the AURORA phase 3 study.

  J Nucl Cardiol, May 2026

• Prevalence, Predictors, and Outcomes of Impaired Myocardial Flow Reserve Among Symptomatic Patients with a Coronary Artery Calcium Score of 0.

  J Nucl Med, May 2026

• Larger baseline body stature predicts one-year amyloid change in cognitively normal older adults enriched with elevated amyloid status.

  J Alzheimers Dis, Apr 2026

• Prolonged β2-agonist treatment enhances muscle-specific glucose uptake in individuals with overweight and obesity: a randomized placebo-controlled trial.

  Nat Commun, Apr 2026

See which targets of this disease your abstract mentions, and go to the people working on them.