Collecting blood and urine samples from people with early polycystic kidney disease
Collects samples and health data from people with early kidney cysts to study markers.
Plain-language title generated from the registry record
Registry title: Early PKD Observational Cohort Study
Key facts
- Where
- Chicago and Kansas City, United StatesSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 4 and 35 years old?
Source: NCT02936791, who can take part
Where in United States
- University of ChicagoChicago, United StatesTaking people
- Children's Mercy HospitalKansas City, United StatesTaking people
- University of Kansas Medical CenterKansas City, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Kansas Medical Center
- Trial code
- NCT02936791
- Record updated
- 27 April 2026
- Original description
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.Read full original descriptionShow less
Early PKD Observational Cohort Study
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.
Inclusion: Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD):; Family history of PKD; All races and ethnic groups; Glomerular filtration rate (GFR) >80 ml/min per 1.73 m2; Inclusion for Healthy Volunteers:; Male or female with no family history of kidney disease; All races and ethnic groups; Normal GFR.
Exclusion: Non-insulin or insulin-dependent diabetes mellitus; Systemic illness (i.e.systemic lupus erythematosus, vasculitis); Unable to provide written informed consent; Unavailable for magnetic resonance imaging (MRI) and blood/urine collection.