Polycystic kidney disease trials in United States

In United States 21 Also abroad 45

21 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Well-Formulated Ketogenic Diet Polycystic Kidney Disease
Where
Columbus
Age
18 years to 65 years
People
20
Run by
Ohio State University
See details and how to joinNCT06325644
Phase 3Taking people
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Where
Ann Arbor, Atlanta, Baltimore, Chicago, Cincinnati, Cleveland, Indianapolis, New Orleans, Pittsburgh, Rochester, Salt Lake City, Washington D.C.
Age
28 days to 18 years
People
20 worldwide
Run by
Otsuka Pharmaceutical Development & Commercialization, Inc.
See details and how to joinNCT04782258 · EU 2023-508218-41-00
Phase 1Taking people
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
Where
Baltimore, Birmingham, Jacksonville, Lenexa, Loma Linda, Orlando, Rochester, San Antonio
Age
18 years to 65 years
People
40 worldwide
Run by
AstraZeneca
See details and how to joinNCT07228364
Phase 2Taking people
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Where
Ann Arbor, Arlington, Atlanta, Bethlehem, Birmingham, Boise, Boston, Chapel Hill, Charleston, Chattanooga, Chicago, Coral Gables, Dallas, Fort Lauderdale, Huntington Park, Idaho Falls, Inverness, Iowa City, Jacksonville, Kansas City, Knoxville, Los Angeles, Miami, Nashville, New Haven, New York, Orange, Philadelphia, Pomona, Rochester, Sanford, San Francisco, Santa Monica, Seattle, Shelby, St Louis, Winston-Salem
Age
18 years to 55 years
People
240 worldwide
Run by
Calico Life Sciences LLC
See details and how to joinNCT06902558 · EU 2024-517143-31-00
Phase 2Taking people
Bempedoic Acid Therapy for Polycystic Kidney Disease
Where
Baltimore, Boston, Burlington
Age
18 years to 60 years
People
120
Run by
Kenneth Hallows
See details and how to joinNCT07282821
No phaseTaking people
ADPKD Patient Registry
Where
Kansas City
People
3,000
Run by
PKD Foundation
See details and how to joinNCT04039061
No phaseTaking people
Managing Depressive Symptoms in ADPKD
Where
Rochester
Age
18 years to 70 years
People
105
Run by
Mayo Clinic
See details and how to joinNCT07745920
No phaseTaking people
ARPKD Database Study
Where
Atlanta, Boston, Cincinnati, Philadelphia, Salt Lake City, Washington D.C.
Age
Up to 18 years
People
200
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT01401998
No phaseTaking people
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study
Where
New Hyde Park, Philadelphia, Rochester, Washington D.C.
Age
Up to 18 years
People
300
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT04338048
No phaseTaking people
Early PKD Observational Cohort Study
Where
Chicago, Kansas City
Age
4 years to 35 years
People
250
Run by
University of Kansas Medical Center
See details and how to joinNCT02936791
No phaseTaking people
Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease
Where
Cleveland
Age
18 years and over
People
20
Run by
Richard Fatica
See details and how to joinNCT07454174
No phaseNot yet taking people in United States
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
Where
Loma Linda
Age
18 years to 65 years
People
30
Run by
Loma Linda University
See details and how to joinNCT06786260
No phaseTaking people
A Prospective Observational Study of Foam Sclerotherapy .
Where
Rochester
Age
18 years to 100 years
People
100
Run by
Mayo Clinic
See details and how to joinNCT04111692
No phaseEnrolling by invitation
Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository
Where
New York
Age
18 years to 100 years
People
100
Run by
Weill Medical College of Cornell University
See details and how to joinNCT03901521
No phaseTaking people
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Where
Rochester
Age
18 years to 30 years
People
40
Run by
Mayo Clinic
See details and how to joinNCT04344769
No phaseTaking people
NOX4 and Related Biomarkers in ADPKD
Where
Rochester
Age
15 years to 40 years
People
60
Run by
Mayo Clinic
See details and how to joinNCT04630613
No phaseTaking people
Imaging Assessments of ARPKD Kidney Disease Progression
Where
Cleveland, Philadelphia
Age
6 years and over
People
60
Run by
The Cleveland Clinic
See details and how to joinNCT07201025
No phaseTaking people
Polycystic Kidney Disease Data Repository
Where
New York
Age
18 years and over
People
1,000
Run by
The Rogosin Institute
See details and how to joinNCT00792155
No phaseTaking people
PKD Clinical and Translational Core Study
Where
Baltimore
Age
18 years and over
People
350
Run by
University of Maryland, Baltimore
See details and how to joinNCT01873235
Phase 2Taking people
Glucagon-Like Peptide-1 Receptor Agonist in ADPKD
Where
Aurora
Age
18 years to 65 years
People
126
Run by
University of Colorado, Denver
See details and how to joinNCT06582875
No phaseTaking people
Amnioinfusion for Fetal Renal Failure
Where
Dallas
People
35
Run by
Fetal Care Center, PLLC
See details and how to joinNCT06728228