Under construction – not a live service
Sign in
Enrolling by invitationNo phase

Collects tissue samples to study genetic changes in polycystic kidney disease

Studies gene changes in adults with autosomal dominant polycystic kidney disease.

Plain-language title generated from the registry record
Registry title: Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository

Key facts

Where
New York, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 100 years old?

Source: NCT03901521, who can take part

Where in United States

  • Weill Cornell MedicineNew York, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Weill Medical College of Cornell University
Trial code
NCT03901521
Record updated
22 January 2026
Original description
This study will analyze the germline and somatic mutations underlying the development of ADPKD in order to better understand the genetic mechanism responsible for the cystic transformation. Once identified, these mutations could help us understand better the mechanism leading to the development of this disease and may explain at least in part the phenotypic variability.Read full original descriptionShow less

Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository

This study will analyze the germline and somatic mutations underlying the development of ADPKD in order to better understand the genetic mechanism responsible for the cystic transformation. Once identified, these mutations could help us understand better the mechanism leading to the development of this disease and may explain at least in part the phenotypic variability.

Inclusion: Males or females; 18 years of age or older; Confirmed diagnosis of ADPKD; Undergoing a native nephrectomy; Willing and able to provide informed consent.

Exclusion: Unable or unwilling to provide informed consent.

ClinicalTrials.gov NCT03901521