Studies brain imaging and tissue in several rare neurodegenerative disorders
Studies brain scans and genetics in people with symptoms suggesting a neurodegenerative disease.
Plain-language title generated from the registry record
Registry title: Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- Mayo ClinicRochester, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT04680130
- Record updated
- 21 November 2025
- Original description
The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.Read full original descriptionShow less
Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.
Inclusion: All participants will be over the age of 21; Have symptoms suggestive of a neurodegenerative and/or related disorder.
Exclusion: Participants will be excluded if they have any concurrent illnesses that could account for all of their symptoms, such as traumatic brain injury, encephalitis, strokes or developmental syndromes; Participants will be excluded if they are medically unstable or are on medications that might affect brain structure or metabolism (e.g. chemotherapy); Participants will be excluded if they have any of the following genetic conditions which can increase the chance of cancer: Cowden disease, Lynch syndrome, Hypogammaglobulinemia, Wiskott-Aldrich syndrome and Down's syndrome; Participants will be excluded if MRI is contraindicated (metal in head, cardiac pace maker, etc), if there is severe claustrophobia, if there are conditions that may confound brain imaging studies (e.g. structural abnormalities, including subdural hematoma, intracranial neoplasm or large cortical infarcts); Women that are pregnant or post-partum and breast-feeding will be excluded.