Tests brain stimulation with language therapy for primary progressive aphasia
Tests brain stimulation combined with language therapy in people with primary progressive aphasia.
Plain-language title generated from the registry record
Registry title: Enhancing Language Function in Primary Progressive Aphasia
Key facts
- Where
- Tucson, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 45 and 80 years old?
Source: NCT04920318, who can take part
Where in United States
- University of ArizonaTucson, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Arizona
- Trial code
- NCT04920318
- Record updated
- 29 November 2024
- Original description
This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.Read full original descriptionShow less
Enhancing Language Function in Primary Progressive Aphasia (PPA) With Transcranial Direct Current Stimulation (tDCS)
This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.
Inclusion: diagnosed with PPA by neurologist or speech-language pathologist; speech-language deficit arising from PPA; native speaker of English Language or equivalent; adequate vision (normal or corrected to normal); adequate hearing.
Exclusion: highly magnetizable metallic implants, including certain dental work; brain surgery in the past; metallic skull plates or implants; excessive use of alcohol or drugs; severe non-linguistic cognitive disturbances impeding language therapy; meeting (Diagnostic and Statistical Manual) DSM-IV criteria for Axis I mood, anxiety, psychotic or substance abuse disorders; neurological disorders besides the ones of interest for the study (e.g., epilepsy); Parkinson's Disease; metallic cardiac pumps; magnetic materials such as surgical clips, implanted electronic perfusion pumps, or any other condition that would preclude proximity to a strong magnetic field; severe systemic disease (e.g., renal failure); family history of epilepsy or other seizure disorders; premorbid psychiatric disease affecting communication; Multiple Sclerosis; contraindications for MRI; pacemakers; valves; clinically significant claustrophobia; poor health; pregnancy; epileptic activity in the past 12 months; skin lesions or skull damage.