Blood Test Study for Eye Damage in People with Diabetes
Looks for a blood marker of eye blood vessel damage in adults with diabetic retinopathy.
Plain-language title generated from the registry record
Registry title: Biomarker of Diabetic Retinopathy
Key facts
- Where
- Carmel and Indianapolis, United StatesSee the 3 sites
Where in United States
- Spring Mill ClinicCarmel, United StatesTaking people
- Eskenazi Eye ClinicIndianapolis, United StatesTaking people
- Glick Eye InstituteIndianapolis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Indiana University
- Trial code
- NCT05079399
- Record updated
- 23 July 2026
- Original description
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.Read full original descriptionShow less
Biomarker of Diabetic Retinopathy
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
Inclusion: Ability to cooperate with imaging procedures; Health status: established type 2 diabetes; No history of panretinal photocoagulation (PRP); No history of treatment with intravitreal agents for past 12 months.
Exclusion: Previous or current malignancy; History of previous vitrectomy; Acute or chronic infection (HIV, hepatitis B or C, tuberculosis); History of organ transplantation; Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion; Cerebral vascular accident or cerebral vascular procedure; Current pregnancy; Presence of a graft (to avoid any effect of the graft).