Home-Based Brain Stimulation Study for People With Huntington's Disease
Tests home-use brain stimulation device for thinking and behavior symptoms in Huntington's disease.
Plain-language title generated from the registry record
Registry title: Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease
Key facts
- Where
- Houston, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT05326451, who can take part
Where in United States
- The University of Texas Health Science Center at HoustonHouston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The University of Texas Health Science Center, Houston
- Trial code
- NCT05326451
- Record updated
- 11 February 2026
- Original description
The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle stages and to assess the efficacy of tDCS for HD-related behavioral, cognitive and other symptomsRead full original descriptionShow less
Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease
The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle stages and to assess the efficacy of tDCS for HD-related behavioral, cognitive and other symptoms
Inclusion: confirmed HD mutation carriers and/or established family history alongside typical symptoms (i.e. chorea) of HD; early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn; exhibit mild to moderate behavioral symptoms defined by severity scores in the PBA-S between 1 and 3 for any of the evaluated symptoms and no symptoms with a severity score of 4; stable doses of medications for at least one month; Have a caregiver willing to be present during tDCS sessions and answer questionnaires; -willingness to participate in the study.
Exclusion: Have risk of suicidal behavior, defined as any suicidal behavior or suicidal ideation of type 4 or type 5 based on the Columbia-Suicide Severity Rating Scale (C-SSRS) in the 3 months prior to screening; unstable medical conditions; history of epilepsy; clinical diagnosis of major cognitive disorder or dementia; -motor/cognitive symptoms related to Alzheimer's disease or Huntington's disease that might impair the ability to assist the participant during the research study; metallic objects in the brain; Have a caregiver willing to be present during tDCS sessions and answer questionnaires; simultaneous participation in other clinical trial; Individuals determined to be incapable of consent per past medical history or via assessment by the study staff at time of consent; Caregiver:.
Participant:.