Speech-Language Training for Language Problems After Stroke or Aphasia
Tests speech-language training in adults with aphasia from stroke or progressive brain disease.
Plain-language title generated from the registry record
Registry title: Enhancing Language Function in Aphasia
Key facts
- Where
- Tucson, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 80 years old?
Source: NCT05443633, who can take part
Where in United States
- University of ArizonaTucson, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Arizona
- Trial code
- NCT05443633
- Record updated
- 9 December 2024
- Original description
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain). This impairment is seen in many aspects of language, including understanding, speaking, reading and writing. It is estimated that about 2 million individuals are currently living with aphasia in the United States. Further, about 200,000 Americans acquire aphasia every year (National Aphasia Association, 2020). Aphasia poses significant impact on the affected individuals and their families. Behavioral treatments that target language deficits have been shown to enhance overall communication skills and life satisfaction among individuals with aphasia. Although there is evidence that suggests that treatment is efficacious for individuals with aphasia, the extent of improvement long-term coupled with the neural patterns among those individuals are largely unknown. The current study aims to investigate the efficacy of language-based treatment and its corresponding neural patterns.Read full original descriptionShow less
Enhancing Language Function in Aphasia Using Behavioral Language Intervention
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain). This impairment is seen in many aspects of language, including understanding, speaking, reading and writing. It is estimated that about 2 million individuals are currently living with aphasia in the United States. Further, about 200,000 Americans acquire aphasia every year (National Aphasia Association, 2020). Aphasia poses significant impact on the affected individuals and their families. Behavioral treatments that target language deficits have been shown to enhance overall communication skills and life satisfaction among individuals with aphasia. Although there is evidence that suggests that treatment is efficacious for individuals with aphasia, the extent of improvement long-term coupled with the neural patterns among those individuals are largely unknown. The current study aims to investigate the efficacy of language-based treatment and its corresponding neural patterns.
Inclusion: Present with speech-language impairment (aphasia) caused by stroke or dementia; A medical diagnosis of primary progressive aphasia (PPA) by a neurologist or physician; Are native speakers of English; Present with no contraindications for MRI; Have adequate (normal or corrected to normal) vision and hearing.
Exclusion: Individuals with highly magnetizable metallic implants, including certain dental work, may be excluded due to image quality in MRI; Individuals who have had a brain surgery in the past; Individuals with implanted metallic skull plates or intracranial implants; Individuals with severe non-linguistic cognitive disturbances impeding language therapy; Individuals diagnosed with mood, anxiety, psychotic or substance abuse disorders; Individuals with other neurological disorders besides the ones of interest for the study (e.g., epilepsy, Multiple Sclerosis, Parkinson's Disease); Individuals with contraindications for MRI. This includes but is not limited to pacemakers, metallic cardiac pumps, valves, magnetic materials such as surgical clips, implanted electronic perfusion pumps, or any other condition that would preclude proximity to a strong magnetic field; Severe systemic disease (e.g., renal failure); Individuals with a history of epileptic activity in the past 12 months; Individuals with a personal or family history of epilepsy or other seizure disorders will not be included in the study; Individuals who have a history of excessive use of alcohol or drugs; Individuals with premorbid psychiatric disease affecting communication; Individuals suffering from clinically significant claustrophobia; Poor overall health; Individuals who are pregnant; Individuals with skin lesions or skull damage.