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Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome

Key facts

Who runs it
Boston Children's Hospital
Where
Boston, United StatesSee the site
Trial code
Status
Completed
People taking part
103 people enrolled
Started
23 Jan 2023
Ended
28 May 2025
Type of study
Interventional, 2 groups
Treatments tested
  • JASPER
  • Psychoeducational Curriculum
Record updated
13 April 2026

Who can take part

Age
36 months to 90 months
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 7 criteriaShow less

Who can take part

  • Confirmed diagnosis of Trisomy 21
  • Age 3-7 years
  • Able to walk independently
  • English speaking
  • Caregiver able to complete either 1:1 virtual coaching sessions or psychoeducational behavioral curriculum

Who cannot take part

  • Mosaic Down syndrome
  • Significant and uncorrected hearing and/or vision problems

Where in United States

  • Boston Children's HospitalBoston, United StatesNo longer taking part

About the trial

What the trial wants to find out

In this study, investigators will study the impact of a 1:1 caregiver coaching intervention using the JASPER (Joint Attention, Symbolic Play, Engagement, Regulation) behavioral therapy curriculum compared to a psychoeducational curriculum that will be provided to caregivers for self-directed learning. Investigators want to determine the impact of both interventions on the child's development and behavior, and caregiver implementation of strategies.

The 2 groups in the trial

  • JASPER Intervention GroupTreatment being tested

    Caregivers receiving the JASPER intervention will undergo weekly virtual 60-minute sessions for 10 weeks conducted via Zoom. The content of the intervention includes teaching and implementation of contingent responding and specific strategies to provide a high-quality response to children's communication, and play behaviors. Caregiver training is completed through review of pre-recorded videos of the caregiver-child dyad each week. The first half of each session will be dedicated to reviewing previous content and feedback on the play recording. The following half will consist of new material. The coaching support includes contingent responding, the parent is also taught to use specific strategies to provide a rich, high-quality response to children's communication, and play behaviors.

    Treatment: JASPER

  • Psychoeducational Curriculum GroupTreatment being tested

    Caregivers receiving the 10 weekly psychoeducational curriculum modules will be provided with the resources via secure email and encouraged to engage with the material a self-directed manner. The psychoeducational modules will include written information about child development, communication and social interaction skills, behavioral principles for managing challenging behavior and strategies for teaching new skills. No direct caregiver-child mediated coaching will be provided. The content of the modules will include information about developmental milestones in this age group for children with DS, behavior management strategy recommendations, positive parenting materials, and materials on increasing engagement through play.

    Treatment: Psychoeducational Curriculum

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
13 April 2026