Measuring Lung Blood Vessel Recovery After Balloon Treatment for Pulmonary Hypertension
Measures lung capillary surface area before and after balloon angioplasty in adults with CTEPH.
Plain-language title generated from the registry record
Registry title: Functional Pulmonary Capillary Surface Area in BPA for CTEPH
Key facts
- Where
- Montreal, CanadaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05719415, who can take part
Where in Canada
- David LanglebenMontreal, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Jewish General Hospital
- Trial code
- NCT05719415
- Record updated
- 23 September 2025
- Original description
Chronic thromboembolic pulmonary hypertension [CTEPH] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall. Many patients with CTEPH are treated with balloon pulmonary angioplasty [BPA] which mechanically opens the narrow pulmonary arteries. It is unclear how much downstream functional pulmonary capillary surface area [FCSA] is recovered during BPA. The investigators plan to measure FCSAIn CTEPH patients, before and after a session of BPA.Read full original descriptionShow less
Assessment of Recovery of Functional Capillary Surface Area in Patients Undergoing a Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension
Chronic thromboembolic pulmonary hypertension [CTEPH] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall. Many patients with CTEPH are treated with balloon pulmonary angioplasty [BPA] which mechanically opens the narrow pulmonary arteries. It is unclear how much downstream functional pulmonary capillary surface area [FCSA] is recovered during BPA. The investigators plan to measure FCSAIn CTEPH patients, before and after a session of BPA.
Inclusion: All patients eligible for balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.
Exclusion: Treatment with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers,; Presence of patent foramen ovale.