Pulmonary arterial hypertension trials in Canada

In Canada 15 Also abroad 305

15 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Sotatercept in Pulmonary Arterial Hypertension
Where
Edmonton
Age
18 years and over
People
27
Run by
University of Alberta
See details and how to joinNCT07140484
Phase 2Taking people
Feasibility Trial for a Right Ventricular Failure Platform Trial
Where
Calgary, Edmonton, London, Ottawa, Vancouver
Age
18 years and over
People
30
Run by
University of Alberta
See details and how to joinNCT06570473
Phase 3Taking people
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Where
Calgary
Age
18 years to 80 years
People
344 worldwide
Run by
Liquidia Technologies, Inc.
See details and how to joinNCT07285655
Phase 3Taking people
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Where
Calgary, London, Ottawa, Toronto
Age
18 years to 75 years
People
330 worldwide
Run by
Gossamer Bio USA, Inc.
See details and how to joinNCT06274801 · EU 2023-506334-75-00
Phase 2Taking people
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Where
Calgary, London
Age
18 years to 80 years
People
40 worldwide
Run by
AllRock Bio, Inc.
See details and how to joinNCT07175038 · EU 2025-522074-37-00
Phase 3Enrolling by invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Where
Calgary, Edmonton, London, Montreal, Québec, Toronto
Age
18 years and over
People
1,000 worldwide
Run by
United Therapeutics
See details and how to joinNCT03683186 · EU 2023-509305-68-00
No phaseTaking people
PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation
Where
Toronto
Age
18 years and over
People
40
Run by
University Health Network, Toronto
See details and how to joinNCT04901884
No phaseNot yet taking people in Canada
Withdrawal of Prostacyclin Pathway Therapy in Patients With Pulmonary Arterial Hypertension Receiving Sotatercept (WATERLOO)
Where
Edmonton
Age
18 years and over
People
78
Run by
University of Alberta
See details and how to joinNCT07700303
Phase 1/2Taking people
DIAG723 in Adults With Hereditary Hemorrhagic Telangiectasia
Where
Laval, Toronto
Age
18 years and over
People
93 worldwide
Run by
Diagonal Therapeutics, Inc.
See details and how to joinNCT07623525
Phase 3Taking people
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Where
Edmonton
Age
18 years to 75 years
People
486 worldwide
Run by
Inhibikase Therapeutics
See details and how to joinNCT07365332 · EU 2024-520218-23-00
No phaseTaking people
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Where
Montreal, Toronto
Age
0 years to 20 years
People
5,000 worldwide
Run by
Duke University
See details and how to joinNCT04278404
No phaseTaking people
MedlyPeds Feasibility Study
Where
Toronto
Age
8 years to 18 years
People
30
Run by
The Hospital for Sick Children
See details and how to joinNCT07556185
No phaseTaking people
Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NEC
Where
Toronto
Age
1 month to 6 months
People
36
Run by
The Hospital for Sick Children
See details and how to joinNCT05636397
No phaseTaking people
Functional Pulmonary Capillary Surface Area in BPA for CTEPH
Where
Montreal
Age
18 years to 75 years
People
40
Run by
Jewish General Hospital
See details and how to joinNCT05719415
No phaseTaking people
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
Where
Edmonton
Age
1 day to 21 years
People
2,500 worldwide
Run by
New York Medical College
See details and how to joinNCT02249923