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Taking people in United StatesNo phase

Young Adult Tobacco/Nicotine and Cannabis Co-use

Key facts

Who runs it
Medical University of South Carolina
Where
Charleston, United StatesSee the site
Trial code
Status
Recruiting
People taking part
350 people, planned
Started
13 May 2024
Expected to end
3 Jan 2028
Type of study
Interventional
Treatments tested
  • Counseling
  • Contingency management
  • Text-based support
Record updated
4 November 2026

Who can take part

Age
18 years to 25 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Between the ages of 18 and 25 years old
  • Must use at least one nicotine or tobacco product (nicotine vaping and/or cigarettes) on at least 20 out of the past 30 days for at least the past 3 months
  • Must express interest in nicotine cessation (all products)
  • Must submit a positive instant-read cotinine sample prior to enrollment
  • Must report use of cannabis on at least 10 out of the past 30 days
  • Must submit a positive instant-read cannabinoid test prior to enrollment
  • Must be able to provide informed consent

Who cannot take part

  • Self-reported use of medications with smoking cessation efficacy
  • Any significant or acutely unstable medical, psychiatric, or substance use problem that would contraindicate research, interfere with safety, compromise data integrity, or preclude consistent study participation
  • Pregnant (self-report) or trying to become pregnant
  • Immediate interest in cannabis cessation or treatment

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 25 years old?

Where in United States

  • Medical University of South Carolina CharlestonCharleston, United StatesContact: Ela WilliamsTaking people

About the trial

What the trial wants to find out

The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt. All participants will receive tobacco/nicotine cessation treatment (smoking and/or vaping treatment) for 12 weeks. To qualify, participants must be between the ages of 18-25 and use tobacco products (smoke cigarettes and/or vape nicotine) and use cannabis (in any form). Participants do not need to be interested in quitting cannabis/marijuana to qualify. This study is being conducted by the Medical University of South Carolina. All procedures are conducted remotely and there is no in-person visits are needed.

The group in the trial

  • Nicotine treatmentOther group

    All participants recieve active nicotine treatment for 12 weeks.

    Treatment: Counseling, Contingency management, and Text-based support

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Impact of Cannabis and Tobacco/Nicotine Product Co-use in Young Adults: Prospective Cessation Evaluation and Substitution
Fit questions
Built from NCT06239350, who can take part
Record updated
4 November 2026