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Following older adults from under-resourced communities with memory and thinking concerns over time

Follows older adults with subjective cognitive decline or mild cognitive impairment from underrepresented communities.

Key facts

Who runs it
Ohio State University
Where
Columbus, United StatesSee the site
Trial code
Registry title
Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog
Status
Enrolling by invitation
People taking part
100 people, planned
Starts
1 Mar 2027
Expected to end
1 Jan 2032
Type of study
Observational
Treatments tested
  • Assessments
  • Neuroimaging volumetric measures
  • Biofluid samples
Record updated
16 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 50 or older with memory or thinking concerns (SCD) or mild cognitive impairment (MCI). It focuses on people from under-resourced or underrepresented communities seen in the Tele-Cog clinic.

Age
50 years and older
Sex
All
Disease stage
Subjective cognitive decline (SCD), or mild cognitive impairment (MCI) with daily functioning mostly intact, diagnosed during a clinical work up. People with dementia cannot join.

Main reasons for not taking part

  • Diagnosis of dementia at the start of the study
  • Not able to give informed consent
  • High risk of a serious emotional or behavioral reaction, as judged by the study doctor
  • Not fluent in English
  • Not willing to agree to the NRI-BBB brain bank and sample storage protocol

The registry criteria, word for word

Show all 10 criteriaShow less

Who can take part

  • Adults ages 50 years and older
  • Diagnosed with subjective cognitive concerns (SCD) or objective cognitive decline with mostly intact functioning (MCI diagnosis) as part of clinical work up
  • Fluent in English
  • Able to provide voluntary informed consent
  • Willing and able to undergo all study procedures
  • Able to delegate, if possible, a study partner. The study partner must be ≥18 years of age and must know the patient well enough to contribute information regarding the patient's daily activities and cognition
  • Must also consent to the Neuroscience Research Institute Brain Bank and Biorepository (NRI-BBB) Banking Protocol (OSU protocol 2020H0512)

Who cannot take part

  • Diagnosis of dementia at baseline
  • High risk of adverse emotional or behavioral reaction based on investigator's clinical evaluation (e.g., evidence of serious personality disorder, antisocial behavior, serious current stressors, lack of meaningful social support)
  • Inability to give informed consent

Where in United States

  • The Ohio State UniversityColumbus, United StatesEnrolling by invitation

About the trial

What the trial wants to find out

The purpose of this study is to establish a longitudinal cohort of older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI): 1) at heightened risk for dementia, and 2) from underrepresented/under-resourced communities to characterize clinical course. This study will utilize the Tele-Cog clinic as a means for recruiting older adults at risk for dementia from under-resourced and underrepresented communities. Successful completion of this project will increase the opportunity for under-resourced and underrepresented communities to participate in cognitive research.

The group in the trial

  • Study Population

    Adults ages 50 years and older who are fluent in English and are diagnosed with subjective cognitive concerns (SCD) or objective cognitive decline with mostly intact functioning (MCI diagnosis) as part of clinical work up

    Treatment: Assessments, Neuroimaging volumetric measures, and Biofluid samples

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
A Prospective, Longitudinal, Observational Cohort Study of Older Adults From Under-resourced/Underrepresented Communities Diagnosed With Subjective Cognitive Decline (SCD) or Mild Cognitive Disorder (MCI) Through Standard of Care Tele-Cog Visits (Tele-Cog)
Plain-language title
Following older adults from under-resourced communities with memory and thinking concerns over timeGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Record updated
16 October 2026