Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
Where
Minneapolis, San Diego
Age
18 years to 60 years
People
160
Run by
United States Naval Medical Center, San Diego
See details and how to joinNCT06413173
Phase 1Taking people
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Where
Bethesda
Age
50 years to 100 years
People
90
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT07169630
No phaseTaking people
Adaptango Performance PRocess for Older Adults Community reHabilitation
Where
Atlanta
Age
18 years and over
People
120
Run by
Emory University
See details and how to joinNCT07824128
No phaseTaking people
Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment
Where
Manhattan, The Bronx
Age
65 years and over
People
30
Run by
Albert Einstein College of Medicine
See details and how to joinNCT07225400
No phaseTaking people
Tennessee Alzheimer's Project
Where
Nashville
Age
60 years and over
People
1,000
Run by
Vanderbilt University Medical Center
See details and how to joinNCT05372172
No phaseNot yet taking people in United States
SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment
Where
San Diego
Age
60 years and over
People
150
Run by
VA Office of Research and Development
See details and how to joinNCT07397182
No phaseTaking people
CMN LIFU for Enhanced Amyloid Reduction (CLEART Study)
Where
San Francisco
Age
65 years and over
People
28
Run by
University of California, San Francisco
See details and how to joinNCT07866768
No phaseTaking people
Treating Insomnia in Mild Cognitive Impairment
Where
Boston
Age
60 years and over
People
30
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT06687161
No phaseTaking people
Telehealth-Adapted Compensatory Training and Intervention for Cognition
Where
Gainesville
Age
65 years to 84 years
People
100
Run by
University of Florida
See details and how to joinNCT07366346
No phaseEnrolling by invitation
Mild Cognitive Impairment and Neuromodulation
Where
Roanoke
Age
55 years to 80 years
People
40
Run by
Virginia Polytechnic Institute and State University
See details and how to joinNCT07691918
Phase 2Taking people
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Where
Atlantis, Aventura, Beaumont, Bolivar, Carlsbad, Chandler, Charlestown, Dallas, Delray Beach, Englewood, Fairfax, Fairway, Farmington Hills, Fort Myers, Foxborough, Gainesville, Golden Valley, Houston, Indianapolis, Irvine, Jacksonville, Kirkland, La Jolla, Maitland, Miami, Ocala, Orlando, Palo Alto, Philadelphia, Plymouth, Portland, Rochester, Round Rock, San Antonio, Scottsdale, Stamford, Tampa, West Palm Beach, Winter Park
Age
55 years to 85 years
People
350 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07589595
No phaseNot yet taking people in United States
A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement
Where
Minneapolis
Age
18 years and over
People
200
Run by
University of Minnesota
See details and how to joinNCT07773493
No phaseNot yet taking people in United States
Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity
Where
Augusta
Age
50 years to 70 years
People
20
Run by
Augusta University
See details and how to joinNCT07741773
No phaseTaking people
Rural Veteran and Care Partner Walking Program
Where
Omaha
Age
19 years to 90 years
People
12
Run by
Creighton University
See details and how to joinNCT07914218
Phase 1Taking people
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Where
Bethesda
Age
18 years to 99 years
People
184
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT04396873
Phase 1Taking people
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Where
Charlestown, Decatur, Durham, Maitland, The Villages, Toms River
Age
50 years to 85 years
People
56 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06297590 · EU 2024-510604-37-00
No phaseTaking people
Combating Alzheimer's Through Sleep and Exercise
Where
Miami
Age
55 years to 80 years
People
60
Run by
University of Miami
See details and how to joinNCT04855630
Phase 2Taking people
Alzheimer's Tau Platform: Master Protocol
Where
Boston, Lexington, Nashville, Phoenix, Providence, San Francisco, Seattle
Age
50 years to 80 years
People
900
Run by
Paul S. Aisen
See details and how to joinNCT06957418
No phaseTaking people
Choose Myself (Before) Losing Myself
Where
Cleveland
Age
18 years and over
People
25
Run by
The Cleveland Clinic
See details and how to joinNCT07846566
No phaseNot yet taking people in United States
Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment
Where
Nashville
Age
18 years and over
People
552
Run by
Miklos Kertai
See details and how to joinNCT07885085
Phase 2Not yet taking people in United States
Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive Impairment
Where
Santa Monica
Age
60 years to 90 years
People
44
Run by
Los Angeles Brain Science Project
See details and how to joinNCT07882901
No phaseTaking people
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
Where
Boston
Age
18 years and over
People
240
Run by
Brigham and Women's Hospital
See details and how to joinNCT07883720
Phase 3Taking people
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Where
Albuquerque, Arlington, Atlanta, Atlantis, Beaumont, Birmingham, Boston, Brownsville, Charleston, Chicago, Clermont, Columbus, Dallas, Decatur, Edinburg, Fairfax, Farmington Hills, Fort Worth, Gainesville, Greensboro, Honolulu, Houston, Imperial, Irvine, Katy, Knoxville, Lady Lake, Laurelton, Long Beach, Los Angeles, Maitland, Marrero, Miami, Nashville, New Haven, Newton, New York, Oakland, Ocala, Orlando, Phoenix, Plymouth Meeting, Portland, Providence, Richmond, Ridgewood, Rio Grande City, Riverside, Rochester, Santa Ana, Sherman Oaks, Springfield, St Louis, Stuart, Summerville, Sun City, Tampa, The Bronx, The Villages, Watertown, Wellington, Winter Park
Age
50 years to 90 years
People
80,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07177352
No phaseEnrolling by invitation
Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog
Where
Columbus
Age
50 years and over
People
100
Run by
Ohio State University
See details and how to joinNCT06542458
No phaseEnrolling by invitation
Digital Lifestyle Coaching for Alzheimer's Disease Prevention in APOE4 Carriers
Where
La Jolla
Age
60 years to 80 years
People
1,200
Run by
Scripps Translational Science Institute
See details and how to joinNCT07646054