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TerminatedNo phase

Using AI and Peer Coaching to Address Racial Disparities Among People Who Use Opioids

Key facts

Who runs it
Friends Research Institute, Inc.
Where
The Bronx, United StatesSee the site
Trial code
Status
Terminated
People taking part
94 people enrolled
Started
28 Mar 2025
Ended
31 Aug 2025
Type of study
Interventional, 3 groupsOne group gets a placebo (a dummy treatment), for comparison.
Treatments tested
  • PRC supported text + AI driven SDH-enhanced text
  • AI driven SDH-enhanced text only
  • Treatment as Usual (TAU)
Record updated
8 September 2026
Why it stopped
Loss of sponsor funding

Who can take part

Age
18 years to 99 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • ≥18 years of age
  • fluent in English and/or Spanish
  • self-reported non-prescription opioid use <30 days prior to consent
  • provision of informed consent
  • planned stay in NYC ≥12 month
  • self-identified Black and/or Latinx race/ethnicity
  • positive urine toxicology for opioids per EMR records
  • diagnosis of OUD per the Diagnostic and Statistical Manual of Mental Disorders-5
  • self-reported interest in initiating buprenorphine in primary care
  • must have a mobile phone data plan

Who cannot take part

  • self-reported receipt of medications for OUD in past 30 days
  • inability to comprehend text content written at a 3rd grade reading level
  • physical or visual disability preventing mobile phone use

Where in United States

  • NYC Health + HospitalsThe Bronx, United States

About the trial

What the trial wants to find out

Black and Latinx people who use opioids are disproportionately impacted by opioid overdose deaths. The proposed study assesses the efficacy of an open source, multimodal artificial intelligence-driven texting tool combined with peer recovery coach-supported text contact that delivers social services, stigma reduction, health habitus, and patient navigation content addressing social determinants of health to enhance receipt of buprenorphine in primary care among emergency department-enrolled Black / Latinx people who use opioids.

The 3 groups in the trial

  • Intervention Arm-1: PRC supported text+ AI driven SDH-enhanced textTreatment being tested

    Participants in this arm will receive a combination of Peer Recovery Coaches (PRCs) supported text-based care/services coordination alongside AI-driven SDH-enhanced text messages to enhance the receipt of buprenorphine in Black/ Latin people who use opioids.

    Treatment: PRC supported text + AI driven SDH-enhanced text

  • Intervention Arm-2: AI driven SDH-enhanced text onlyTreatment being tested

    Participants in this arm will receive AI-driven SDH-enhanced text messages to enhance the receipt of buprenorphine in Black/ Latin people who use opioids. Unlike Arm-1, this intervention does not include the additional support and coordination provided by Peer Recovery Coaches.

    Treatment: AI driven SDH-enhanced text only

  • Control Arm 3- Treatment as UsualPlacebo, for comparison

    Control Arm-3 will receive treatment as usual (i.e., verbal instructions, NYC Dept of Health pamphlets detailing access to OUD and social services, health system smartphone application EMR patient portal).

    Treatment: Treatment as Usual (TAU)

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Leveraging Social Determinants Via Artificial Intelligence and Peer Coaching to Address Racial Disparities in Primary Care Among People Who Use Opioids
Record updated
8 September 2026