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Opioid use disorder

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Where research stands todayUpdated 15 Nov 2026
Trial-stage treatments you can join–open now
in United States
Studies published in the last 12 months00 in people · 0 in animals · 0 in the lab
Support organisations2organisations
in United States1 helpline
Offer tissue or dataGive a sample or your health data to research.Approved treatmentsMedicines approved for opioid use disorder around the world.“Miracle cure” fact checkerSaw a cure online? Check it before you pay.

Trial-stage treatments and research studies you can join

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Get notified of new trialsUnited States, all cities, all phases
Your ageShows only trials that take people your age.
Phase
  1. Trial-stage treatmentPhase 1Soon in United States
    Phase 1 trial: mitragynine
    Overland Park, United StatesAge 18 to 65
  2. Trial-stage treatmentPhase 4Soon in United States
    Phase 4 trial: Injectable buprenorphine, Sublingual Buprenorphine (SUBOXONE, Zubsolv, or generic…
    San Francisco, United StatesAge 18+
  3. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized…
    New York, United StatesAlso The BronxAge 21 to 75
  4. Trial-stage treatmentPhase 4Soon in United States
    Tests long-acting HIV prevention and opioid treatment drugs in people in custody

    Tests long-acting HIV prevention and opioid use treatment drugs in people held in custody.

    Durham, United StatesAge 18+
  5. Trial-stage treatmentPhase 1Taking people
    Early Phase 1 trial: Regional Anesthesia, Hydromorphone Patient Controlled Analgelsic
    Milwaukee, United StatesAge 18 to 40
  6. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Ketamine
    La Jolla, United StatesAlso Salt Lake CityAge 18+
  7. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Brenipatide, Buprenorphine
    Baltimore, United StatesAlso Boston, Bradenton, Charleston, Charlottesville, Chicago, Columbus, Daytona Beach, DeSoto, …Age 18 to 75
  8. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Lidocaine, Lidocaine and Dexamethasone
    Galveston, United StatesAge 18 to 100
  9. Trial-stage treatmentPhase 4Soon in United States
    Phase 4 trial: Buprenorphine, Oxycodone
    Winston-Salem, United StatesAge 18 to 80
  10. Trial-stage treatmentSoon in United States
    Clinical trial: KIOS App
    San Antonio, United StatesAge 18+
  11. Trial-stage treatmentPhase 1Soon in United States
    Early Phase 1 trial: Alcohol
    Columbus, United StatesAge 21 to 65
  12. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Cebranopadol
    Houston, United StatesAlso North CantonAge 18 to 65
  13. Trial-stage treatmentPhase 1Taking people
    Early Phase 1 trial: 400 mg Cannabidiol, 800 mg Cannabidiol, 1200 mg Cannabidiol
    West Haven, United StatesAge 18 to 70
  14. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Treatment with Ketamine, Treatment with Very Low Dose Ketamine
    Baltimore, United StatesAge 18 to 65
  15. Trial-stage treatmentPhase 1Taking people
    Phase 1 trial: Methadone hydrochloride
    Philadelphia, United StatesAge 18+
  16. Trial-stage treatmentTaking people
    Clinical trial: Connections mHealth Application
    Madison, United StatesAge 18+
  17. Trial-stage treatmentPhase 1Soon in United States
    Phase 1 trial: Cannabis, Intranasal Opioid Agonist, Oral Opioid Agonist
    Lexington, United StatesAge 18 to 55
  18. Trial-stage treatmentTaking people
    Tests repetitive magnetic brain stimulation for depression in adults

    Tests magnetic brain stimulation over the orbitofrontal cortex in adults with depression.

    Houston, United StatesAge 18 to 64
  19. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Semaglutide
    Boston, United StatesAge 18+
  20. Trial-stage treatmentTaking people
    Clinical trial: Transcranial Direct Current Stimulator (tDCS)
    New York, United StatesAge 18 to 60

Support organisations

Patient organisations and helplines in United States, for you and your family.

We have no organisations for this disease listed in United States yet. General support there is below.

General support in United States

  • 988 Suicide & Crisis Lifeline

    US national 24/7 free and confidential lifeline for anyone in suicidal crisis or emotional distress, reachable by calling or texting 988 or by chat.

    988lifeline.org
  • MedlinePlus

    Free, easy-to-read health information service of the US National Library of Medicine (NIH) on diseases, conditions, drugs and wellness.

    medlineplus.gov

International organisations

Patient organisation umbrella bodies

Offer tissue or data

There are three ways to help research move faster.

Give tissue or bloodA biobank stores your sample so many research teams can use it.No open programme yet
Share your health dataA patient registry collects your health data, without your name, for research.How to join
Take part as a healthy volunteerStudies also need people without the disease, for comparison. Family and friends can help.Volunteer

“Miracle cure” fact checker

Social media spreads misinformation. Paste what you read here, and we'll tell you whether there is scientific evidence behind it.

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Before you pay for anything, ask three things

  1. Is there a published study in people?
  2. Can I have the full price in writing?
  3. What does my doctor say?

“Cures” others already fact-checked

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