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Taking people in United StatesNo phase

Rural Smoking Cessation

Key facts

Who runs it
Masonic Cancer Center, University of Minnesota
Where
Durham and Minneapolis, United StatesSee the 2 sites
Trial code
Status
Recruiting
People taking part
544 people, planned
Started
17 Mar 2026
Expected to end
31 Aug 2029
Type of study
Interventional, 3 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • Nicoderm CQ nicotine patch
  • Nicorette Nicotine Lozenges
Record updated
13 November 2026

Who can take part

Age
21 years and older
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • ≥ 21 years
  • smoke ≥ 5 cigarettes per day
  • daily access to their own iPhone/Android smartphone or tablet

Who cannot take part

  • past 30-day NRT use or contraindications listed on the NRT labels
  • currently pregnant/breastfeeding

Where in United States

  • Duke UniversityDurham, United StatesContact: Devon Noonan, PhDTaking people
  • Masonic Cancer CenterMinneapolis, United StatesContact: Dana Carroll, PhD, MPHTaking people

About the trial

What the trial wants to find out

Understanding ways to help people who live in rural areas quit smoking is a public health priority. quitting smoking among rural people who smoke is a critical public health concern. People in rural areas smoke at higher rates than those in urban areas, experience high rates of smoking caused cancers and deaths. We are recruiting rural people from around the country to better understand how different quit smoking methods can improve a person's chances of successfully quitting smoking.

The 3 groups in the trial

  • Intervention ConditionTreatment being tested

    Weekly text and email messages referring to Smokefree.gov, NRT Starter kit, free 2-week supply of patches (Nicoderm CQ in either 21 or 14 mg nicotine) and lozenges (Nicorette Nicotine Lozenges, Mint Flavor in either 4 or 2 mg nicotine) with NRT education plus referral to where to request more NRT.

    Treatment: Nicoderm CQ nicotine patch and Nicorette Nicotine Lozenges

  • Control ConditionNo study treatment, for comparison

    Weekly text and email messages referring to Smokefree.gov

  • RHE - Intervention ConditionNo study treatment, for comparison

    Weekly text and email messages on reduced harm or exposure (RHE) tobacco products.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Evaluating Population-Based Strategies for Rural Smoking Cessation
Record updated
13 November 2026