Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.
Key facts
- Who runs it
- Medical College of Wisconsin
- Where
- Milwaukee, United StatesSee the 2 sites
- Trial code
- Status
- Recruiting
- Phase
- Early phase 1
- People taking part
- 20 people, planned
- Started
- 16 Jan 2025
- Expected to end
- 31 Dec 2028
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Regional Anesthesia
- Hydromorphone Patient Controlled Analgelsic
- Epidural local anesthetic infusion
- Record updated
- 5 November 2026
Who can take part
- Age
- 18 years to 40 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Inclusion criteria include being a parturient with Substance use disorder (SUD) and age 18-35
Who cannot take part
- Exclusion criteria include having a diagnosed medical condition(allergies to medication, pathology such as severe aortic stenosis excluding patients from receiving an epidural etc) that will exempt patient from intervention arm of the study
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 40 years old?
Where in United States
- Froedtert HospitalMilwaukee, United StatesContact: Meredith Albrecht, MD,PhDNot yet recruiting
- Froedtert Hospital Milwaukee, Wisconsin 53226Milwaukee, United StatesContact: Christopher FadumiyeTaking people
About the trial
What the trial wants to find out
The purpose of this study is to investigate the efficacy of three different modalities of post-operative pain control in parturient with opioid use disorders. The investigators aim to determine whether the different approach utilized show better outcomes with pain management and if there are any association with reduction of symptoms of anxiety, depression, and overall well-being.
The 3 groups in the trial
- Transverse abdominal Plane(TAP) Block with long acting ExparelExisting treatment, for comparison
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Treatment: Regional Anesthesia
- Postoperative Epidural infusion for 24-36hrsExisting treatment, for comparison
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Treatment: Epidural local anesthetic infusion
- Hydromorphone Patient Controlled Analgesia (PCA),Preservative free Morphine via epidural for 36hrsExisting treatment, for comparison
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Treatment: Hydromorphone Patient Controlled Analgelsic
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications: Efficacy and Safety Outcomes.
- Fit questions
- Built from NCT06617949, who can take part
- Record updated
- 5 November 2026