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Taking people in United StatesNo phase

Technology Assisted Motivational Interviewing

Key facts

Who runs it
University of California, San Francisco
Where
San Francisco, United StatesSee the 2 sites
Trial code
Status
Recruiting
People taking part
440 people, planned
Started
22 Sept 2025
Expected to end
31 May 2027
Type of study
Interventional, 2 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • TAMI Coach
Record updated
23 October 2025

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

  • A current Primary Care Provider patient
  • Age 18 or older
  • Smoke at least 1 cigarette per day for the past 7 consecutive days (and at least 100 lifetime)
  • Have a digital device (phone, laptop, tablet)
  • Moderately proficient in English
  • Able to participate for 6-month trial

Who cannot take part

  • Current use of Nicotine Replacement Therapy or smoking cessation pharmacotherapy
  • Cognitive impairment that would preclude informed consent
  • Current participation in a smoking cessation program

Where in United States

  • San Francisco General HospitalSan Francisco, United StatesContact: Jason Satterfield, PhDTaking people
  • UCSF Adult Primary Care Mt. Zion ClinicSan Francisco, United StatesContact: Jason Satterfield, PhDTaking people

About the trial

What the trial wants to find out

Building on our successful pilot work to develop a Motivational Interviewing (MI)-capable chatbot and cessation coach, the investigators propose to address the problems of intrinsic motivation and social barriers to smoking cessation by evaluating a highly scalable and easily accessible digital-coaching intervention that 1) promotes readiness to change using a technology-assisted MI (TAMI) chatbot, 2) provides compelling and accessible multilingual education about smoking cessation tools, and 3) develops a tailored quit plan addressing social barriers to treatment initiation and sustainment.

The 2 groups in the trial

  • Technology Assisted Motivational Interviewing (TAMI)Treatment being tested

    Individuals randomized to TAMI will interact with the fully automated, web-based MI-chatbot for the 6-month study period. Patients who continue to smoke will receive up to two text messages per week with the chatbot URL link to initiate additional conversations always beginning with an assessment of readiness to change but "remembering" prior conversations much like a clinician. Individuals in the preparation stage will move directly to EBP education, tailoring a quit plan and boosting both self-efficacy and outcome expectancies. Patients with sufficient confidence will be encouraged to set a quit date. Patients will be encouraged to include their PCP and/or state quitline. TAMI will provide support proximal to the quit date including guidance through common obstacles. TAMI will check back to assess treatment initiation, treatment sustainment (and/or cessation), or relapse. Patients who are unable to quit (or who relapse) will be encouraged to restart conversations with TAMI.

    Treatment: TAMI Coach

  • Usual CareNo study treatment, for comparison

    Individuals randomized to the Usual Care (UC) condition will receive a detailed educational handout on the health risks associated with smoking and information on Evidence Based Practice's (EBP) for cessation using the standard "Kick-It California" materials. Additional materials and referral resources regarding depression, stress, and other common barriers will be provided to all UC participants. Any UC individual can choose to quit at any time but they will not have access to TAMI. While this is not an "active" treatment condition, the handout and recurring assessments (at 3 and 6mo) may serve as reminders about the importance of quitting and may assist with finding support for co-occurring conditions or social needs.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Technology Assisted Motivational Interviewing Randomized Controlled Trial
Record updated
23 October 2025