Tests a special diet in adults with polycystic kidney disease
Tests a targeted diet for kidney cyst growth in adults with polycystic kidney disease.
Plain-language title generated from the registry record
Registry title: Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
Key facts
- Where
- Loma Linda, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06786260, who can take part
Where in United States
- Loma Linda University HealthLoma Linda, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Loma Linda University
- Trial code
- NCT06786260
- Record updated
- 30 January 2026
- Original description
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in serum and urinary biomarkers, total kidney volume (TKV), and cyst progression in subjects with autosomal dominant polycystic kidney disease (ADPKD).Read full original descriptionShow less
Di-PKD: A Pilot Trial of a 12-Month Targeted Dietary Intervention on Cyst Progression in Patients With Autosomal Dominant Polycystic Kidney Disease
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in serum and urinary biomarkers, total kidney volume (TKV), and cyst progression in subjects with autosomal dominant polycystic kidney disease (ADPKD).
Researchers will compare the results of subjects in the study diet (interventional) arm to the results of subjects in the regular diet (control) arm.
Inclusion: Confirmed diagnosis of ADPKD; Genetic testing confirmation of PKD1 or PKD2; eGFR >30mL/1.73m2; Willingness to adhere to a preconditioning diet for 1 week and ability to complete the study; Mayo Clinic Imaging Classification (MCIC): 1C, 1D, 1E.
Exclusion: History of dietary non-adherence; Comorbidities that could interfere with participation (Diabetes, Heart Failure (EF<30%) Advanced Chronic Kidney Disease (CKD) Stage 4 and higher); Subjects on Tolvaptan.